(±)17-HDHA - Moligand™, ≥98%, 100μg/ml in ethanol , CAS No.90780-52-2

CAS: 90780-52-2 Cat. No.: H345262 분자식: C₂₂H₃₂O₃ 분자량: 344.49

GRADE & PURITY Moligand™, ≥98%, 100μg/ml in ethanol

Synonyms

(4Z,7Z,10Z,13Z,15E,19Z)-17-Hydroxydocosahexaenoic acid | LMFA07010952 | SR-01000946909-1 | 17-HDoHE | SCHEMBL10026728 | (.+/-.)17-HDoHE | 17-Hdhe | SR-01000946909 | WPKPLSFHHBBLRY-UHFFFAOYSA-N | 17-Hydroxydocosahexaenoate | CHEBI:72637 | (+/-)-17-hydroxy-

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

개요

(±)17-HDoHE is an autoxidation product of docosahexaenoic acid (DHA)|in vitro|. It has been found to be produced from incubations of DHA in rat brain, intestinal microsomes and liver. (±)17-HDoHE has been shown to inhibit U-46619-induced rabbit and rat aortic smooth muscle contraction (IC|50|= 4.9 and 7.2 μM, respectively). It is also a potential marker of oxidative stress in brain and retina where DHA is abundant.

Specifications

동의어

(4Z,7Z,10Z,13Z,15E,19Z)-17-Hydroxydocosahexaenoic acid | LMFA07010952 | SR-01000946909-1 | 17-HDoHE | SCHEMBL10026728 | (.+/-.)17-HDoHE | 17-Hdhe | SR-01000946909 | WPKPLSFHHBBLRY-UHFFFAOYSA-N | 17-Hydroxydocosahexaenoate | CHEBI:72637 | (+/-)-17-hydroxy-

사양 및 순도

Moligand™, ≥98%, 100μg/ml in ethanol

생화학 및 생리적 메커니즘

17-HDHA is a DHA-derived specialized proresolving mediator (SPM). 17-HDHA enhances the antibody-mediated immune response against influenza virus. 17-HDHA enhances the differentiation of B cells toward the CD27+ CD38+ antibody-secreting cell phenotype, the

보관 조건

Store at -20°C

배송

Ice chest + Ice pads

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등급

Moligand™

작업 유형

INHIBITOR

순수함

≥98%

이름과 식별자

• 정식 스마일: CCC=CCC(C=CC=CCC=CCC=CCC=CCCC(=O)O)O
• IUPAC Name: (4Z,7Z,10Z,13Z,15E,19Z)-17-hydroxydocosa-4,7,10,13,15,19-hexaenoic acid
• InChIKey: SWTYBBUBEPPYCX-VIIQGJSXSA-N
• INCHI: 1S/C22H32O3/c1-2-3-15-18-21(23)19-16-13-11-9-7-5-4-6-8-10-12-14-17-20-22(24)25/h3,5-8,11-16,19,21,23H,2,4,9-10,17-18,20H2,1H3,(H,24,25)/b7-5-,8-6-,13-11-,14-12-,15-3-,19-16+
• 이성체 SMILES: CC/C=C\CC(/C=C/C=C\C/C=C\C/C=C\C/C=C\CCC(=O)O)O
• 분자량: 344.49
• Reaxy-Rn: 20137078
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=20137078&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Lipids and lipid-like molecules
    • 분류 Fatty Acyls
      • Subclass Fatty acids and conjugates

• Kingdom: Organic compounds
• Superclass: Lipids and lipid-like molecules
• 분류: Fatty Acyls
• Subclass: Fatty acids and conjugates
• Intermediate Tree Nodes: Not available
• Direct Parent: Very long-chain fatty acids
• Alternative Parents: Hydroxy fatty acids Unsaturated fatty acids Secondary alcohols Monocarboxylic acids and derivatives Carboxylic acids Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Very long-chain fatty acid - Hydroxy fatty acid - Unsaturated fatty acid - Secondary alcohol - Monocarboxylic acid or derivatives - Carboxylic acid - Carboxylic acid derivative - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Alcohol - Aliphatic acyclic compound
• 설명: This compound belongs to the class of organic compounds known as very long-chain fatty acids. These are fatty acids with an aliphatic tail that contains at least 22 carbon atoms.
• External Descriptors: Docosanoids

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

화학 및 물리적 특성

• 끓는점(°C): 78° C
• 분자량: 344.500 g/mol
• XLogP3: 5.100
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 14
• Exact Mass: 344.235 Da
• Monoisotopic Mass: 344.235 Da
• Topological Polar Surface Area: 57.500 Ų
• Heavy Atom Count: 25
• Formal Charge: 0
• Complexity: 493.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 6
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 6
• Covalently-Bonded Unit Count: 1

자주 묻는 질문

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 90780-52-2, the molecular formula is C22H32O3, and the molecular weight is 344.49 g/mol. InChIKey SWTYBBUBEPPYCX-VIIQGJSXSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.