2,3-디하이드록시벤조산 - ≥98%(HPLC) , CAS No.303-38-8

CAS: 303-38-8 Cat. No.: D154867 분자식: C7H6O4 분자량: 154.12 Beilstein Registry Number: 2209120 EC 번호: 206-139-5
주문 가능
GRADE & PURITY ≥98%(HPLC)
Synonyms
1,2-DIHYDROXYBENZENE-3-CARBOXYLIC ACID | Catechol-3-carboxylic acid | DHBA | CHEBI:18026 | 2,3-Dihydroxybenzoic acid;Catecholcarboxylic acid;NSC 27435 | Benzoic acid, dihydroxy- | PS-3013 | SR-01000761414 | AC-2985 | EINECS 206-139-5 | Benzoic acid,3-dihy
Storage
Room temperature
Shipped In
보통
★
Size
USA
독일 (EU)*
Price
Qty
5g
D154867-5g
4 재고 있음
—
US$54.90
25g
D154867-25g
4 재고 있음
—
US$156.90
100g
D154867-100g
5 재고 있음
—
US$435.90
Enter a quantity for the sizes you want to add.
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Why this grade

≥98%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Room temperature Ships 보통 Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 18 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

개요

2,3-디하이드록시벤조산은 과수혈 쥐 모델에서 경구용 효과적인 철분 킬레이트 약물로 밝혀졌습니다. 이 물질은 브루셀라 아보르투스균에 의해 생성되는 모노카테콜 사이드로포어입니다.
2,3-디하이드록시벤조산은 전기화학, 분광광도법 및 자기법에 의해 염기성 매질에서 망간과 지방족 및 방향족 폴리하이드록시 리간드의 복합체를 연구하는 데 사용되었습니다. 인간 병원균인 비브리오 불니피쿠스의 저철분 배양물에서 벌브니박틴이라는 새로운 사이드로포어를 분리하는 데 사용되었습니다. 피라세탐의 공결정 형성 및 물리화학적 특성에 대한 위치 이성질체의 영향을 연구하기 위한 공결정 형성제로 사용되었습니다.

Specifications

동의어
1,2-DIHYDROXYBENZENE-3-CARBOXYLIC ACID | Catechol-3-carboxylic acid | DHBA | CHEBI:18026 | 2,3-Dihydroxybenzoic acid;Catecholcarboxylic acid;NSC 27435 | Benzoic acid, dihydroxy- | PS-3013 | SR-01000761414 | AC-2985 | EINECS 206-139-5 | Benzoic acid,3-dihy
사양 및 순도
≥98%(HPLC)
생화학 및 생리적 메커니즘
2,3-디하이드록시벤조산은 과수혈 쥐 모델에서 경구용 효과적인 철분 킬레이트 약물로 밝혀졌습니다. 브루셀라 아보르투스균에 의해 생성되는 모노카테콜 사이드로포어입니다.
보관 조건
Room temperature
배송
보통
순수함
≥98%(HPLC)
이름과 식별자
Pubchem Sid488179482
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488179482
정식 스마일C1=CC(=C(C(=C1)O)O)C(=O)O
IUPAC Name2,3-dihydroxybenzoic acid
InChIKeyGLDQAMYCGOIJDV-UHFFFAOYSA-N
INCHI1S/C7H6O4/c8-5-3-1-2-4(6(5)9)7(10)11/h1-3,8-9H,(H,10,11)
이성체 SMILES C1=CC(=C(C(=C1)O)O)C(=O)O
WGK 독일 2
RTECS DG8576490
분자량 154.12
Beilstein 2209120
Reaxy-Rn 2209117
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2209117&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
분류Benzene and substituted derivatives
SubclassBenzoic acids and derivatives
Intermediate Tree Nodes Hydroxybenzoic acid derivatives - Salicylic acid and derivatives
Direct ParentSalicylic acids
Alternative Parents Benzoic acids  Catechols  Benzoyl derivatives  1-hydroxy-4-unsubstituted benzenoids  1-hydroxy-2-unsubstituted benzenoids  Vinylogous acids  Monocarboxylic acids and derivatives  Carboxylic acids  Organooxygen compounds  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAromatic homomonocyclic compounds
Substituents Salicylic acid - Benzoic acid - Benzoyl - Catechol - 1-hydroxy-4-unsubstituted benzenoid - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Vinylogous acid - Carboxylic acid derivative - Carboxylic acid - Monocarboxylic acid or derivatives - Organic oxygen compound - Hydrocarbon derivative - Organic oxide - Organooxygen compound - Aromatic homomonocyclic compound
설명This compound belongs to the class of organic compounds known as salicylic acids. These are ortho-hydroxylated benzoic acids.
External Descriptors dihydroxybenzoic acid
3D 구조
상호 작용 화학 구조 모델





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ATXN2 Tbio Ataxin-2 (54410 Activities)
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관련 대상(비인간)
Sele Selectin E (1 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Selp P-selectin (7 Activities)
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Mmp9 Matrix metalloproteinase 9 (38 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HD1 Histone deacetylase (38 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PC-12 (7051 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
lef Anthrax lethal factor (7585 Activities)
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ARG1 Arginase-1 (70 Activities)
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작용 메커니즘
인증서(CoA, COO, BSE/TSE 및 분석 차트)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

13 results found

Lot NumberCertificate Type날짜항목
C2616051Certificate of AnalysisJun 02, 2023 D154867
F2315850Certificate of AnalysisJun 02, 2023 D154867
F2315853Certificate of AnalysisJun 02, 2023 D154867
F2315854Certificate of AnalysisJun 02, 2023 D154867
F2315856Certificate of AnalysisJun 02, 2023 D154867
F2315859Certificate of AnalysisJun 02, 2023 D154867
K2518046Certificate of AnalysisJun 02, 2023 D154867
A2225121Certificate of AnalysisDec 30, 2021 D154867
A2225123Certificate of AnalysisDec 30, 2021 D154867
A2225159Certificate of AnalysisDec 30, 2021 D154867
B2317114Certificate of AnalysisDec 30, 2021 D154867
I2219414Certificate of AnalysisDec 30, 2021 D154867
L2216892Certificate of AnalysisDec 30, 2021 D154867

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화학 및 물리적 특성
용해성Soluble in water, methanol and dimethyl sulfoxide.
녹는점(°C)204-206°C
분자량154.120 g/mol
XLogP31.200
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count4
Rotatable Bond Count1
Exact Mass154.027 Da
Monoisotopic Mass154.027 Da
Topological Polar Surface Area77.800 Ų
Heavy Atom Count11
Formal Charge0
Complexity157.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Citations of This Product
참고 문헌
1. Dali Fu, Haodong Wang, Tan Wang, Chunming Xu, Yehua Han.  (2023)  Structural insights into variation of intramolecular acid site using phase transition experiments and computation.  AICHE JOURNAL,  70  (4): (e18342).  [PMID:] [10.1002/aic.18342]
2. Xiaomei Yao, Yingbo Fang, Xiaochen Cui, Xian Cheng, Zixia Cheng.  (2023)  Dielectric Barrier Discharge Plasma Coupled with Cobalt Oxyhydroxide for Methylene Blue Degradation.  Toxics,  11  (9): (763).  [PMID:37755773] [10.3390/toxics11090763]
3. Fanghua Guo, Li Peng, Hua Xiong, Rong Tsao, Hua Zhang, Li Jiang, Yong Sun.  (2023)  Bioaccessibility and transport of lentil hull polyphenols in vitro, and their bioavailability and metabolism in rats.  FOOD RESEARCH INTERNATIONAL,      [PMID:37087206] [10.1016/j.foodres.2023.112634]
4. Huiqun Fan, Mingshun Chen, Taotao Dai, Lizhen Deng, Chengmei Liu, Wei Zhou, Jun Chen.  (2023)  Phenolic compounds profile of Amomum tsaoko Crevost et Lemaire and their antioxidant and hypoglycemic potential.  Food Bioscience,      [PMID:] [10.1016/j.fbio.2023.102508]
5. Yunan Zhang, Yu Duan, Jin Su, Lixin Liu, Yanru Feng, Lili Wu, Lei Zhang, Yunjie Zhang, Dongyu Zou, Yingli Liu.  (2021)  Inspiration for revival of old drugs: improving solubility and avoiding hygroscopicity of pipemidic acid by forming two pharmaceutical salts based on charge-assisted hydrogen bond recognitions.  NEW JOURNAL OF CHEMISTRY,  45  (42): (19704-19713).  [PMID:] [10.1039/D1NJ03314J]
6. Deying Meng, Huangmei Zhou, Jianhua Xu, Sanjun Zhang.  (2021)  Studies on the interaction of salicylic acid and its monohydroxy substituted derivatives with bovine serum albumin.  CHEMICAL PHYSICS,      [PMID:] [10.1016/j.chemphys.2021.111182]
7. Lei Xu, Shaoyu Tang, Dan Li, Xiao Ma, Yunqing Zhu, Jianjiang Lu, Junfeng Niu.  (2021)  Electrochemical degradation of tris(2-chloroethyl) phosphate by metal-oxide-coated Ti anodes: Kinetics, toxicity and mechanism.  SEPARATION AND PURIFICATION TECHNOLOGY,      [PMID:] [10.1016/j.seppur.2021.118489]
8. Ren Jingyu, Li Jie, Lv Lei, Wang Jian.  (2020)  Regeneration of [Bmim]BF4 ionic liquid by ozonation: hydrogen bond roles, synergistic effect, and DFT calculation.  ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH,  28  (10): (12909-12917).  [PMID:33097991] [10.1007/s11356-020-11298-7]
9. Lei Xu, Junfeng Niu, Hongbin Xie, Xiao Ma, Yunqing Zhu, John Crittenden.  (2020)  Effective degradation of aqueous carbamazepine on a novel blue-colored TiO2 nanotube arrays membrane filter anode.  JOURNAL OF HAZARDOUS MATERIALS,      [PMID:33254736] [10.1016/j.jhazmat.2020.123530]
10. Mingfang Zhu, Hongqing Ye, Mushen Lai, Jianshan Ye, Rui Li, Wenhao Zhang, Huanru Liang, Rongkun Zhu, Huajun Fan, Shi Chen.  (2019)  The gold nanoparticle sensitized pRGO-MWCNTs grid modified carbon fiber microelectrode as an efficient sensor system for simultaneous detection of three dihydroxybenzoic acid isomers.  ELECTROCHIMICA ACTA,      [PMID:] [10.1016/j.electacta.2019.134765]
11. Lei Xu, Xiao Ma, Junfeng Niu, Jie Chen, Chengzhi Zhou.  (2019)  Removal of trace naproxen from aqueous solution using a laboratory-scale reactive flow-through membrane electrode.  JOURNAL OF HAZARDOUS MATERIALS,      [PMID:31255850] [10.1016/j.jhazmat.2019.05.085]
12. Yitao Li, Xingdong Shi, Zhi Zhang, Yazhou Peng.  (2019)  Enhanced coagulation by high-frequency ultrasound in Microcystis aeruginosa-laden water: Strategies and mechanisms.  ULTRASONICS SONOCHEMISTRY,      [PMID:30712852] [10.1016/j.ultsonch.2019.01.022]
13. Haifeng Zhou, Malin Cui, Yuan Zhao, Chan Wang, Qijun Song.  (2017)  Preparation of Nitrogen and FeP Doped Carbon Nanotubes for Selective and Simultaneous Electrochemical Detection of Dihydroxybenzoic Acid Isomers.  ELECTROCHIMICA ACTA,      [PMID:] [10.1016/j.electacta.2017.05.045]
14. Cui Xiaoqing, Geng Haoyuan, Guo Huanying, Wang Lei, Zhu Zihan, Zhang Yaqi, Chen Panpan, Wang Xiao, Sun Chenglong.  (2024)  Visualizing the transdermal delivery of berberine loaded within chitosan microneedles using mass spectrometry imaging.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,  416  (29): (6869-6877).  [PMID:39400576] [10.1007/s00216-024-05584-3]
15. Fei Qi, Zequan Zeng, Hongbin Lu, Wenhao Si, Yanbiao Liu, Zhanggen Huang, Yuting Niu.  (2025)  Se/N Co-doped carbon for boosted organic oxidation via periodate activation: Impact of electronic structure reconstruction.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.166563]
16. Xiaoqing Cui, Shiping Chen, Haoyuan Geng, Panpan Chen, Yaqi Zhang, Min Li, Xiao Wang, Chenglong Sun.  (2025)  Integrating Thiolated Mass Tags with Immuno-Mass Spectrometry Imaging to Map the Spatial Signatures of Functional Proteins in Cancer Tissues.  ANALYTICAL CHEMISTRY,      [PMID:40839076] [10.1021/acs.analchem.5c01135]
17. Yu Qiao, Huajing Zhou, Lingxiang Zhao, Liang He, Rongrong Miao, Zilian Liu, Qingqing Guan.  (2025)  The selective 3e− ORR pathway induced by differential polarization of surface -OH by adjacent heterodinuclear metals realizes the directed conversion of radicals.  JOURNAL OF ENVIRONMENTAL MANAGEMENT,      [PMID:40561922] [10.1016/j.jenvman.2025.126248]
18. Yue Wang, Jingyi Lin, Yonghuan Zhao, Weiguang Lv, Bo Liang, Peihua Li, Kaisheng Zhang, Xing-jiu Huang.  (2026)  Substituent-controlled phenoxy radicals drive cross-coupling transformation of tetracycline on δ-MnO2.  WATER RESEARCH,      [PMID:42531873] [10.1016/j.watres.2026.126580]
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자주 묻는 질문

What is the purity of this product, and how is it determined?
This product is supplied at ≥98% purity, determined by HPLC. Lot-specific values are stated on the Certificate of Analysis.
How should this product be stored?
Store at room temperature.
How is this product shipped?
This product ships under standard ambient conditions. No temperature-controlled packaging is required.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 303-38-8, the molecular formula is C7H6O4, and the molecular weight is 154.12 g/mol. InChIKey GLDQAMYCGOIJDV-UHFFFAOYSA-N.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

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