4E1RCat - ≥95% , CAS No.328998-25-0

CAS: 328998-25-0 Cat. No.: E345401 분자식: C28H18N2O6 분자량: 478.45
주문 가능
등급 & 순도 ≥95%
Synonyms
4-[(3E)-3-[[5-(4-nitrophenyl)furan-2-yl]methylidene]-2-oxo-5-phenylpyrrol-1-yl]benzoic acid
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
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E345401-5mg
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10mg
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25mg
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US$69.90
50mg
E345401-50mg
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100mg
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≥95% 최소한의 기준선 간섭이 필요한 민감한 크로마토그래피 및 분석 워크플로우용.

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보관 및 배송

Store at -20°C Ice chest + Ice pads 출고. 정확한 사양은 로트별 COA를 확인하세요.

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품질 문서

SDS, COA, 데이터시트, 사양서를 다운로드할 수 있습니다. 로트별 COA는 로트 번호 조회를 통해 확인할 수 있습니다.

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문헌적 근거

크로마토그래피, 유기 합성 및 교차 커플링 반응 분야의 동료 심사 논문 0편에서 인용되었습니다.

개요

4E1RCat is an inhibitor of protein translation that has been shown to prevent eIF4E:eIF4G and eIF4E:4E-BP1 interaction. This compound blocks assembly of the eIF4F complex and inhibits cap-dependent translation.


Application:

4E1RCat was used to inhibit new protein synthesis in transformed primary chicken embryo fibroblasts.

사양

동의어
4-[(3E)-3-[[5-(4-nitrophenyl)furan-2-yl]methylidene]-2-oxo-5-phenylpyrrol-1-yl]benzoic acid
사양 및 순도
≥95%
보관 조건
Store at -20°C
배송
Ice chest + Ice pads
이 제품은 콜드 체인 배송이 필요합니다.지상 및 기타 경제 서비스는 사용할 수 없습니다.
작업 유형
INHIBITOR
순수함
≥95%
제품 특성
pKa
pKa: 4.33 (Predicted)
이름과 식별자
Pubchem Sid
Pubchem Sid Url
https://pubchem.ncbi.nlm.nih.gov/substance/504772432
정식 스마일
C1=CC=C(C=C1)C2=CC(=CC3=CC=C(O3)C4=CC=C(C=C4)[N+](=O)[O-])C(=O)N2C5=CC=C(C=C5)C(=O)O
IUPAC Name
4-[(3Z)-3-[[5-(4-nitrophenyl)furan-2-yl]methylidene]-2-oxo-5-phenylpyrrol-1-yl]benzoic acid
InChIKey
BBQRBOIMSKMFFO-PGMHBOJBSA-N
INCHI
1S/C28H18N2O6/c31-27-21(16-24-14-15-26(36-24)19-6-12-23(13-7-19)30(34)35)17-25(18-4-2-1-3-5-18)29(27)22-10-8-20(9-11-22)28(32)33/h1-17H,(H,32,33)/b21-16-
이성체 SMILES
C1=CC=C(C=C1)C2=C/C(=C/C3=CC=C(O3)C4=CC=C(C=C4)[N+](=O)[O-])/C(=O)N2C5=CC=C(C=C5)C(=O)O
WGK 독일
3
분자량
478.45
Reaxy-Rn
39858347
Reaxys-RN_link_address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=39858347&ln=

문서

📋 안전 데이터 시트(SDS)

위험성, 취급, 보관 및 규제 준수를 포괄하는 종합 문서.

<<<<<<< HEAD SDS 다운로드 → ======= SDS 다운로드 → >>>>>>> release248-p3

✅ 분석 성적서(COA)

로트별 품질 데이터. 로트 번호를 입력하여 정확한 COA를 확인하세요.

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📊 데이터시트

제품 사양 및 응용 분야에 대한 빠른 참조 요약.

데이터시트 보기 →

🔬 사양서

이 등급의 전체 품질 특성 및 합격 기준.

사양서 보기 →

고급 데이터

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
분류Benzene and substituted derivatives
SubclassBenzoic acids and derivatives
Intermediate Tree Nodes Not available
Direct ParentAcylaminobenzoic acid and derivatives
Alternative Parents Phenylpyrrolines  Benzoic acids  Nitrobenzenes  Benzoyl derivatives  Nitroaromatic compounds  Tertiary carboxylic acid amides  Pyrroles  Furans  Heteroaromatic compounds  Lactams  Oxacyclic compounds  Propargyl-type 1,3-dipolar organic compounds  Azacyclic compounds  Carboxylic acids  Organic oxoazanium compounds  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  Organic salts  Organic zwitterions  Organonitrogen compounds  
Molecular FrameworkAromatic heteromonocyclic compounds
Substituents Acylaminobenzoic acid or derivatives - 1-phenylpyrroline - 2-phenylpyrroline - Benzoic acid - Nitrobenzene - Nitroaromatic compound - Benzoyl - Furan - Heteroaromatic compound - Pyrrole - Pyrroline - Tertiary carboxylic acid amide - Carboxamide group - Lactam - C-nitro compound - Organic nitro compound - Organic 1,3-dipolar compound - Organoheterocyclic compound - Propargyl-type 1,3-dipolar organic compound - Azacycle - Oxacycle - Allyl-type 1,3-dipolar organic compound - Carboxylic acid derivative - Organic oxoazanium - Carboxylic acid - Organic salt - Organic oxygen compound - Organic nitrogen compound - Organic oxide - Hydrocarbon derivative - Organonitrogen compound - Organic zwitterion - Organooxygen compound - Carbonyl group - Aromatic heteromonocyclic compound
설명This compound belongs to the class of organic compounds known as acylaminobenzoic acid and derivatives. These are derivatives of amino benzoic acid derivatives where the amine group is N-acylated.
External Descriptors Not available
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상호 작용 화학 구조 모델





관련 대상(비인간)
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
작용 메커니즘
인증서(CoA, COO, BSE/TSE 및 분석 차트)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

6 results found

Lot NumberCertificate Type날짜항목
I2622055I2622055Certificate of AnalysisOct 10, 2026 E345401
G2206192G2206192Certificate of AnalysisApr 03, 2025 E345401
G2206193G2206193Certificate of AnalysisApr 03, 2025 E345401
G2206194G2206194Certificate of AnalysisApr 03, 2025 E345401
G2206195G2206195Certificate of AnalysisApr 03, 2025 E345401
G2206196G2206196Certificate of AnalysisApr 03, 2025 E345401
화학 및 물리적 특성
용해성Soluble in DMSO (≥5 mg/ml).
굴절률n20D1.71 (Predicted)
끓는점(°C)764.78° C at 760 mmHg (Predicted)
녹는점(°C)310.74° C (Predicted)
분자량478.500 g/mol
XLogP35.300
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count5
Exact Mass478.116 Da
Monoisotopic Mass478.116 Da
Topological Polar Surface Area117.000 Ų
Heavy Atom Count36
Formal Charge0
Complexity901.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds1
Covalently-Bonded Unit Count1
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