(±)5-HETE - Moligand™, ≥95%, 100 µg/ml in ethanol , CAS No.71030-39-2

CAS: 71030-39-2 Cat. No.: H336046 분자식: C₂₀H₃₂O₃ 분자량: 320.5

GRADE & PURITY Moligand™, ≥95%, 100 µg/ml in ethanol

Synonyms

SCHEMBL44451 | SR-01000946911 | (6E,8Z,11Z,14Z)-5-hydroxy-6,8,11,14-eicosatetraenoicacid | 1-Ethyl-1,2-hydro-6-hydroxy-4-methyl-2-oxo-3-pyridinecarbonitrile | 5-Hete | 5-Hete, (+/-)- | BDBM50024447 | (??)5-HETE | HETE-5(S) | UNII-92JQY74TBX | 5-hydroxy-6E

Storage

Protected from light,Store at -20°C

Shipped In

Ice chest + Ice pads

개요

(±)5-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid, and it is a racemic mixture. It induces the aggregation of isolated neutrophils with an IC|50|value of 200 nM.

Specifications

동의어

SCHEMBL44451 | SR-01000946911 | (6E,8Z,11Z,14Z)-5-hydroxy-6,8,11,14-eicosatetraenoicacid | 1-Ethyl-1,2-hydro-6-hydroxy-4-methyl-2-oxo-3-pyridinecarbonitrile | 5-Hete | 5-Hete, (+/-)- | BDBM50024447 | (??)5-HETE | HETE-5(S) | UNII-92JQY74TBX | 5-hydroxy-6E

사양 및 순도

Moligand™, ≥95%, 100 µg/ml in ethanol

보관 조건

Protected from light,Store at -20°C

배송

Ice chest + Ice pads

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등급

Moligand™

순수함

≥95%

이름과 식별자

• Pubchem Sid: 528753470
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/528753470
• 대체 CAS: 73307-52-5
• 분자량: 320.5

관련 대상(인간)

ALOX5 Tclin Arachidonate 5-lipoxygenase (6568 Activities)

Discover Target: ALOX5

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

작용 메커니즘

화학 및 물리적 특성

• 용해성: Soluble in water (0.8 mg/ml at 25° C), DMSO (~50 mg/ml), DMF (~50 mg/ml), ethanol, and PBS(pH7.2).
• 감도: air & light sensitive
• 분자량: 320.500 g/mol
• XLogP3: 5.200
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 14
• Exact Mass: 320.235 Da
• Monoisotopic Mass: 320.235 Da
• Topological Polar Surface Area: 57.500 Ų
• Heavy Atom Count: 23
• Formal Charge: 0
• Complexity: 392.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 4
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 4
• Covalently-Bonded Unit Count: 1

참고 문헌

1. FengShengyong , MaEnhao , NaXiaona , WangZongmei , TaiWanbo , BaoXinhui , WangMao , ChangHan , WuBaolei , LiuMiaoxi , LiJuzhen , ShiHuicheng , YangCeli , XiMenglu , YangHaibing , LiYuhan , ZhuYibin , WangPenghua , ZhaoLing , ZhaoAi , ChengGong.  (2025)  Dietary supplementation of arachidonic acid promotes humoral immunity.  EMBO Molecular Medicine,      [PMID:40940568] [10.1038/s44321-025-00310-7]

자주 묻는 질문

What is the purity of this product?

This product is supplied at ≥95% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?20 °C, protected from light. The material is light-sensitive — keep it in its original opaque or amber container.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 71030-39-2, the molecular formula is C20H32O3, and the molecular weight is 320.5 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.