≥98%, A solution in ethanol for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Protected from light,Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
5(S),15(S)-DiHETE is biosynthesised in human eosinophils. It has shown to enhance neutrophil degranulation and serve as a potent chemotaxin for human eosinophils
5(S),15(S)-DiHETE is supplied as a solution in ethanol.To change the solvent, simply evaporate the ethanol under a gentle stream of nitrogen and immediately add the solvent of choice. Solvents such as DMSO and dimethyl formamide purged with an inert gas can be used. The solubility of 5(S),15(S)-DiHETE in these solvents is approximately 50 mg/ml.
5(S),15(S)-DiHETE is sparingly soluble in aqueous buffers. For maximum solubility in aqueous buffers, the ethanolic solution of 5(S).15(S)-DiHETE should be diluted with the aqueous buffer of choice. The solubility of 5(S),15(S)-DiHETE in PBS (pH 7.2) is approximately 1 mg/ml. We do not recommend storing the aqueous solution for more than one day.
.
| 정식 스마일 | CCCCCC(C=CC=CCC=CC=CC(CCCC(=O)O)O)O |
|---|---|
| IUPAC Name | (5S,6E,8Z,11Z,13E,15S)-5,15-dihydroxyicosa-6,8,11,13-tetraenoic acid |
| InChIKey | UXGXCGPWGSUMNI-BVHTXILBSA-N |
| INCHI | 1S/C20H32O4/c1-2-3-9-13-18(21)14-10-7-5-4-6-8-11-15-19(22)16-12-17-20(23)24/h5-8,10-11,14-15,18-19,21-22H,2-4,9,12-13,16-17H2,1H3,(H,23,24)/b7-5-,8-6-,14-10+,15-11+/t18-,19+/m0/s1 |
| 이성체 SMILES | CCCCC[C@@H](/C=C/C=C\C/C=C\C=C\[C@H](CCCC(=O)O)O)O |
| 분자량 | 336.47 |
| Reaxy-Rn | 50462418 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=50462418&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Lipids and lipid-like molecules |
| 분류 | Fatty Acyls |
| Subclass | Eicosanoids |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Hydroxyeicosatetraenoic acids |
| Alternative Parents | Long-chain fatty acids Hydroxy fatty acids Unsaturated fatty acids Secondary alcohols Monocarboxylic acids and derivatives Carboxylic acids Organic oxides Hydrocarbon derivatives Carbonyl compounds |
| Molecular Framework | Aliphatic acyclic compounds |
| Substituents | Hydroxyeicosatetraenoic acid - Long-chain fatty acid - Hydroxy fatty acid - Fatty acid - Unsaturated fatty acid - Secondary alcohol - Carboxylic acid derivative - Carboxylic acid - Monocarboxylic acid or derivatives - Organic oxide - Organic oxygen compound - Alcohol - Hydrocarbon derivative - Carbonyl group - Organooxygen compound - Aliphatic acyclic compound |
| 설명 | This compound belongs to the class of organic compounds known as hydroxyeicosatetraenoic acids. These are eicosanoic acids with an attached hydroxyl group and four CC double bonds. |
| External Descriptors | Hydroxy/hydroperoxyeicosatetraenoic acids |
| 용해성 | Soluble in ethanol, water (>1 mg/ml) at 25° C, DMSO (~50 mg/ml), DMF (~50 mg/ml), and PBS pH 7.2 (~1 mg/ml). |
|---|---|
| 감도 | Air sensitive;Light sensitive |
| 굴절률 | n20D1.53 |
| 끓는점(°C) | 78° C |
| 분자량 | 336.500 g/mol |
| XLogP3 | 4.000 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 14 |
| Exact Mass | 336.23 Da |
| Monoisotopic Mass | 336.23 Da |
| Topological Polar Surface Area | 77.800 Ų |
| Heavy Atom Count | 24 |
| Formal Charge | 0 |
| Complexity | 421.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 2 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 4 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 4 |
| Covalently-Bonded Unit Count | 1 |
L2205508