7ACC2 - Moligand™, ≥98% , Inhibitor of Monocarboxylate transporter 2, CAS No.1472624-85-3, Inhibitor of Monocarboxylate transporter 2

CAS: 1472624-85-3 Cat. No.: A413605 분자식: C18H15NO4 분자량: 309.32
주문 가능
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
Synonyms
7-(benzyl(methyl)amino)-2-oxo-2H-chromene-3-carboxylic acid | 7-[Benzyl(methyl)amino]-2-oxo-2H-chromene-3-carboxylic acid | 7-Aminocarboxycoumarin 2 | 7-ACC2 | 7-[Methyl(phenylmethyl)amino]-2-oxo-2H-1-benzopyran-3-carboxylic acid | 7-(N-Benzyl-N-methylami
Storage
Protected from light,Store at -20°C
Shipped In
Ice chest + Ice pads
Size
USA
독일 (EU)*
Price
Qty
5mg
A413605-5mg
2 재고 있음

US$139.90

US$209.90
저장 US$70.00 (33.35%)
10mg
A413605-10mg
3 재고 있음

US$251.90

US$377.90
저장 US$126.00 (33.34%)
25mg
A413605-25mg
2 재고 있음

US$550.90

US$826.90
저장 US$276.00 (33.38%)
50mg
A413605-50mg
1 재고 있음

US$991.90

US$1,487.90
저장 US$496.00 (33.34%)
Enter a quantity for the sizes you want to add.
🧪

Why this grade

Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Protected from light,Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

개요

Information

7ACC2 7ACC2 is a potent inhibitor of mitochondrial pyruvate transport 1 (MCT1) with an IC50 value of 10 nM for lactate uptake in SiHa human cervix carcinoma cells.


Targets

MCT1

Specifications

동의어
7-(benzyl(methyl)amino)-2-oxo-2H-chromene-3-carboxylic acid | 7-[Benzyl(methyl)amino]-2-oxo-2H-chromene-3-carboxylic acid | 7-Aminocarboxycoumarin 2 | 7-ACC2 | 7-[Methyl(phenylmethyl)amino]-2-oxo-2H-1-benzopyran-3-carboxylic acid | 7-(N-Benzyl-N-methylami
사양 및 순도
Moligand™, ≥98%
생화학 및 생리적 메커니즘
7ACC2 is a potent inhibitor of mitochondrial pyruvate transport 1 (MCT1) with an IC50 value of 10 nM for lactate uptake in SiHa human cervix carcinoma cells.
보관 조건
Protected from light,Store at -20°C
배송
Ice chest + Ice pads
이 제품은 콜드 체인 배송이 필요합니다.지상 및 기타 경제 서비스는 사용할 수 없습니다.
등급
Moligand™
작업 유형
INHIBITOR
작동 메커니즘
Inhibitor of Monocarboxylate transporter 2
순수함
≥98%
제품 특성
ALogP3.235
hba_count3
회전 가능한 결합4
이름과 식별자
Pubchem Sid504772288
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504772288
정식 스마일CN(CC1=CC=CC=C1)C2=CC3=C(C=C2)C=C(C(=O)O3)C(=O)O
IUPAC Name7-[benzyl(methyl)amino]-2-oxochromene-3-carboxylic acid
InChIKeyXTKDQPFUOFAMRL-UHFFFAOYSA-N
INCHI1S/C18H15NO4/c1-19(11-12-5-3-2-4-6-12)14-8-7-13-9-15(17(20)21)18(22)23-16(13)10-14/h2-10H,11H2,1H3,(H,20,21)
이성체 SMILES CN(CC1=CC=CC=C1)C2=CC3=C(C=C2)C=C(C(=O)O3)C(=O)O
분자량 309.32
Reaxy-Rn 24094831
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=24094831&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassPhenylpropanoids and polyketides
분류Coumarins and derivatives
SubclassNot available
Intermediate Tree Nodes Not available
Direct ParentCoumarins and derivatives
Alternative Parents 1-benzopyrans  Phenylmethylamines  Dialkylarylamines  Benzylamines  Pyranones and derivatives  Aralkylamines  Heteroaromatic compounds  Lactones  Amino acids  Oxacyclic compounds  Carboxylic acids  Organooxygen compounds  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents Coumarin - Benzopyran - 1-benzopyran - Benzylamine - Phenylmethylamine - Tertiary aliphatic/aromatic amine - Dialkylarylamine - Pyranone - Aralkylamine - Monocyclic benzene moiety - Pyran - Benzenoid - Heteroaromatic compound - Tertiary amine - Amino acid or derivatives - Amino acid - Lactone - Organoheterocyclic compound - Oxacycle - Carboxylic acid derivative - Carboxylic acid - Hydrocarbon derivative - Organic oxide - Organonitrogen compound - Organic oxygen compound - Organic nitrogen compound - Amine - Organooxygen compound - Aromatic heteropolycyclic compound
설명This compound belongs to the class of organic compounds known as coumarins and derivatives. These are polycyclic aromatic compounds containing a 1-benzopyran moiety with a ketone group at the C2 carbon atom (1-benzopyran-2-one).
External Descriptors Not available
3D 구조
상호 작용 화학 구조 모델





관련 대상(인간)
SLC16A7 Tchem Monocarboxylate transporter 2 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SLC16A3 Tchem Monocarboxylate transporter 4 (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SiHa (2051 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Liver microsomes (16955 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Liver (3974 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
관련 대상(비인간)
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasma (328 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
작용 메커니즘
인증서(CoA, COO, BSE/TSE 및 분석 차트)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

4 results found

Lot NumberCertificate Type날짜항목
F2230055Certificate of AnalysisApr 03, 2025 A413605
F2230059Certificate of AnalysisApr 03, 2025 A413605
F2230060Certificate of AnalysisApr 03, 2025 A413605
F2230061Certificate of AnalysisApr 03, 2025 A413605
화학 및 물리적 특성
용해성Solubility (25°C) In vitro DMSO: 62 mg/mL (200.43 mM); Water: Insoluble; Ethanol: Insoluble;
감도light sensitive
DMSO(mg/mL) 최대 용해도62
DMSO(mM) 최대 용해도200.439674123885
물(mg/mL) 최대 용해도<1
분자량309.300 g/mol
XLogP33.800
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count4
Exact Mass309.1 Da
Monoisotopic Mass309.1 Da
Topological Polar Surface Area66.800 Ų
Heavy Atom Count23
Formal Charge0
Complexity495.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
솔루션 계산기
리뷰

고객 리뷰

자주 묻는 질문

What is the purity of this product?
This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.
What is Moligand??
Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.
How should this product be stored?
Store at ?20 °C, protected from light. The material is light-sensitive — keep it in its original opaque or amber container.
How is this product shipped?
This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 1472624-85-3, the molecular formula is C18H15NO4, and the molecular weight is 309.32 g/mol. InChIKey XTKDQPFUOFAMRL-UHFFFAOYSA-N.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

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