8-Chloroadenosine - ≥98%(HPLC) , CAS No.34408-14-5

CAS: 34408-14-5 Cat. No.: C287342 분자식: C10H12ClN5O4 분자량: 301.69
주문 가능
등급 & 순도 ≥98%(HPLC)
Synonyms
SCHEMBL987728 | (2R,3R,4S,5R)-2-(6-amino-8-chloropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol | UNII-PA05MFH3I7 | NSC-354258 | Q27286427 | AKOS024284395 | PA05MFH3I7 | 2-(6-amino-8-chloropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol | AC-32299 | 8-Chloro
Storage
Protected from light,Store at -20°C
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이 등급을 선택하는 이유

≥98%(HPLC) 최소한의 기준선 간섭이 필요한 민감한 크로마토그래피 및 분석 워크플로우용.

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보관 및 배송

Protected from light,Store at -20°C Ice chest + Ice pads 출고. 정확한 사양은 로트별 COA를 확인하세요.

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품질 문서

SDS, COA, 데이터시트, 사양서를 다운로드할 수 있습니다. 로트별 COA는 로트 번호 조회를 통해 확인할 수 있습니다.

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문헌적 근거

크로마토그래피, 유기 합성 및 교차 커플링 반응 분야의 동료 심사 논문 0편에서 인용되었습니다.

사양

동의어
SCHEMBL987728 | (2R,3R,4S,5R)-2-(6-amino-8-chloropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol | UNII-PA05MFH3I7 | NSC-354258 | Q27286427 | AKOS024284395 | PA05MFH3I7 | 2-(6-amino-8-chloropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol | AC-32299 | 8-Chloro
사양 및 순도
≥98%(HPLC)
생화학 및 생리적 메커니즘
Nucleoside analog; metabolizedin vivoto 8-Chloro-ATP. Incorporates into RNA during transcription and inhibits RNA synthesis. Exhibits cytotoxicity in MM.1S, RPMI-8226 and U266 cancer cell lines; induces G2/M cell cycle arrest and mitotic catastrophe in A5
보관 조건
Protected from light,Store at -20°C
배송
Ice chest + Ice pads
이 제품은 콜드 체인 배송이 필요합니다.지상 및 기타 경제 서비스는 사용할 수 없습니다.
작업 유형
ACTIVATOR
순수함
≥98%(HPLC)
이름과 식별자
Pubchem Sid
정식 스마일
C1=NC(=C2C(=N1)N(C(=N2)Cl)C3C(C(C(O3)CO)O)O)N
IUPAC Name
(2R,3R,4S,5R)-2-(6-amino-8-chloropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
InChIKey
MHDPPLULTMGBSI-UUOKFMHZSA-N
INCHI
1S/C10H12ClN5O4/c11-10-15-4-7(12)13-2-14-8(4)16(10)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,13,14)/t3-,5-,6-,9-/m1/s1
이성체 SMILES
C1=NC(=C2C(=N1)N(C(=N2)Cl)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)N
분자량
301.69
Reaxy-Rn
1227660
Reaxys-RN_link_address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1227660&ln=

문서

📋 안전 데이터 시트(SDS)

위험성, 취급, 보관 및 규제 준수를 포괄하는 종합 문서.

<<<<<<< HEAD SDS 다운로드 → ======= SDS 다운로드 → >>>>>>> release248-p3

✅ 분석 성적서(COA)

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📊 데이터시트

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🔬 사양서

이 등급의 전체 품질 특성 및 합격 기준.

사양서 보기 →

고급 데이터

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassNucleosides, nucleotides, and analogues
분류Purine nucleosides
SubclassNot available
Intermediate Tree Nodes Not available
Direct ParentPurine nucleosides
Alternative Parents Glycosylamines  Pentoses  6-aminopurines  Aminopyrimidines and derivatives  N-substituted imidazoles  Imidolactams  Aryl chlorides  Tetrahydrofurans  Heteroaromatic compounds  Secondary alcohols  Oxacyclic compounds  Azacyclic compounds  Primary amines  Primary alcohols  Organopnictogen compounds  Organochlorides  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents Purine nucleoside - N-glycosyl compound - Glycosyl compound - Pentose monosaccharide - 6-aminopurine - Purine - Imidazopyrimidine - Aminopyrimidine - Imidolactam - Pyrimidine - N-substituted imidazole - Monosaccharide - Aryl halide - Aryl chloride - Heteroaromatic compound - Tetrahydrofuran - Imidazole - Azole - Secondary alcohol - Oxacycle - Azacycle - Organoheterocyclic compound - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Hydrocarbon derivative - Primary amine - Primary alcohol - Organooxygen compound - Organonitrogen compound - Organochloride - Organohalogen compound - Amine - Alcohol - Aromatic heteropolycyclic compound
설명This compound belongs to the class of organic compounds known as purine nucleosides. These are compounds comprising a purine base attached to a ribosyl or deoxyribosyl moiety.
External Descriptors Not available
3D 구조
상호 작용 화학 구조 모델





작용 메커니즘
인증서(CoA, COO, BSE/TSE 및 분석 차트)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

10 results found

Lot NumberCertificate Type날짜항목
C2414381C2414381Certificate of AnalysisFeb 01, 2024 C287342
C2414382C2414382Certificate of AnalysisFeb 01, 2024 C287342
C2414383C2414383Certificate of AnalysisFeb 01, 2024 C287342
C2414384C2414384Certificate of AnalysisFeb 01, 2024 C287342
C2414395C2414395Certificate of AnalysisFeb 01, 2024 C287342
C2414396C2414396Certificate of AnalysisFeb 01, 2024 C287342
C2414397C2414397Certificate of AnalysisFeb 01, 2024 C287342
C2414398C2414398Certificate of AnalysisFeb 01, 2024 C287342
C2414399C2414399Certificate of AnalysisFeb 01, 2024 C287342
C2414400C2414400Certificate of AnalysisFeb 01, 2024 C287342
화학 및 물리적 특성
용해성Solvent:water, Max Conc. mg/mL: 6.03, Max Conc. mM: 20 with gentle warming; Solvent:DMSO, Max Conc. mg/mL: 30.17, Max Conc. mM: 100
감도Light sensitive
분자량301.690 g/mol
XLogP3-0.100
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count8
Rotatable Bond Count2
Exact Mass301.058 Da
Monoisotopic Mass301.058 Da
Topological Polar Surface Area140.000 Ų
Heavy Atom Count20
Formal Charge0
Complexity367.000
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
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