9-Phenanthrol - Moligand™, technical grade , Channel blocker of TRPM4, CAS No.484-17-3, Channel blocker of TRPM4

CAS: 484-17-3 Cat. No.: P136335 분자식: C₁₄H₁₀O 분자량: 194.23 EC 번호: 207-602-4 PubChem CID: 10229

등급 & 순도 Moligand™, Technical grade

Synonyms

Phenanthren-9-ol|9-Phenanthrenol|phenanthrene-9-ol|9-Hydroxyphenanthrene; NSC 50554|9-Phenanthrenol; 9-Hydroxyphenanthrene; NSC 50554;|9-Phenanthrol-D8|9-Hydroxyphenanthrene|9-PHENANTHROL

Storage

Room temperature

Shipped In

Normal

사양

동의어

Phenanthren-9-ol | 9-Phenanthrenol | phenanthrene-9-ol | 9-Hydroxyphenanthrene; NSC 50554 | 9-Phenanthrenol; 9-Hydroxyphenanthrene; NSC 50554; | 9-Phenanthrol-D8 | 9-Hydroxyphenanthrene | 9-PHENANTHROL

사양 및 순도

Moligand™, technical grade

생화학 및 생리적 메커니즘

Selective TRPM4 blocker (IC 50 = 20 μM). Modulates smooth muscle contraction. Reduces LPS-induced cell death. Promotes angiogenesis. Shows cardioprotective and anti-ischemic effects in vivo.

보관 조건

Room temperature

배송

Normal

등급

Moligand™, 기술 등급

작업 유형

CHANNEL BLOCKER

작동 메커니즘

Channel blocker of TRPM4

참고

Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

이름과 식별자

Pubchem Sid

504751916

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/504751916

정식 스마일

C1=CC=C2C(=C1)C=C(C3=CC=CC=C23)O

IUPAC Name

phenanthren-9-ol

InChIKey

DZKIUEHLEXLYKM-UHFFFAOYSA-N

INCHI

1S/C14H10O/c15-14-9-10-5-1-2-6-11(10)12-7-3-4-8-13(12)14/h1-9,15H

이성체 SMILES

C1=CC=C2C(=C1)C=C(C3=CC=CC=C23)O

WGK 독일

3

RTECS

SF8288000

PubChem CID

10229

분자량

194.23

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • 분류 Phenanthrenes and derivatives
      • Subclass Phenanthrols

• Kingdom: Organic compounds
• Superclass: Benzenoids
• 분류: Phenanthrenes and derivatives
• Subclass: Phenanthrols
• Intermediate Tree Nodes: Not available
• Direct Parent: Phenanthrols
• Alternative Parents: Naphthols and derivatives 1-hydroxy-2-unsubstituted benzenoids Organooxygen compounds Hydrocarbon derivatives
• Molecular Framework: Aromatic homopolycyclic compounds
• Substituents: Phenanthrol - 1-naphthol - 2-naphthol - Naphthalene - 1-hydroxy-2-unsubstituted benzenoid - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Aromatic homopolycyclic compound
• 설명: This compound belongs to the class of organic compounds known as phenanthrols. These are compounds containing a phenanthrene (or its hydrogenated derivative) to which a hydroxyl group is attached.
• External Descriptors: phenanthrol

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

관련 대상(인간)

TRPM4 Tchem Transient receptor potential cation channel subfamily M member 4 (0 Activities)

Discover Target: TRPM4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HL-60 (67320 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HCT-116 (91556 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

작용 메커니즘

화학 및 물리적 특성

• 분자량: 194.230 g/mol
• XLogP3: 3.600
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 194.073 Da
• Monoisotopic Mass: 194.073 Da
• Topological Polar Surface Area: 20.200 Ų
• Heavy Atom Count: 15
• Formal Charge: 0
• Complexity: 225.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

자주 묻는 질문

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

What does technical grade mean?

technical grade indicates that the material has been processed and tested for specialty industrial processing. Specifications focus on the impurities that affect performance in that application — for example, metal content for electronics, particle size for batteries, refractive index for optics, or moisture content for moisture-sensitive processes.

How should this product be stored?

Store at room temperature.

How is this product shipped?

This product ships under standard ambient conditions. No temperature-controlled packaging is required.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 484-17-3, the molecular formula is C14H10O, and the molecular weight is 194.23 g/mol. InChIKey DZKIUEHLEXLYKM-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.