α-Thrombin , CAS No.9002-04-4

CAS: 9002-04-4 Cat. No.: np330890 분자식: C₁₂H₁₀ClN₃S 분자량: 263.75 EC 번호: 232-648-7 PubChem CID: 65045

GRADE & PURITY Bioactive, ActiBioPure™, Native, High Performance, EnzymoPure™, from Human plasma; ≥2700 NIH U/mg protein; Pre-lyophilization Protein Concentration: See COA

Accession #

P00734

Bioactivity

≥2700 NIH U/mg protein

개요

The Human Thrombin was activated from homogeneous human prothrombin by activation with Factor Xa, Factor Va, and phospholipid. These activating enzymes were removed after activation. Complete activation was observed on SDS-PAGE. This activated enzyme has a minimum activity of 2,700 NIH units/mg when compared to NIH standard thrombin.

Extinction Coefficient (1%) = 18.3 

The above protein was purified from Human plasma units that test negative for antibodies to HBc, HCV, HIV 1/2, HTLV-I/II, and non reactive for HBsAg, HIV-1 RNA, HCV RNA, HBV DNA and Syphilis by FDA approved tests. Donors are screened for CJD.

Protein is for research use only; not for human use.

Specifications

Product Name

α-Thrombin , CAS No.9002-04-4

동의어

Human Alpha Thrombin | Human α-Thrombin | Human alpha-Thrombin Native Protein | Factor IIa, Human Plasma | Coagulation factor IIa | F2 | PT | THPH1 | RPRGL2

등급

ActiBioPure™, Bioactive, High Performance, Native, EnzymoPure™

사양 및 순도

Bioactive, ActiBioPure™, Native, High Performance, EnzymoPure™, from Human plasma; ≥2700 NIH U/mg protein; Pre-lyophilization Protein Concentration: See COA

생화학 및 생리적 메커니즘

Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing. Activates coagulation

생체 활성

≥2700 NIH U/mg protein

가입 번호

P00734

예상 분자량

37 kDa

CAS

9002-04-4

효소 커미션 번호

EC 3.4.21.5

분자 유형

Enzyme

Product Line

biological_products

제품 특성

나크레스

NA.54

보관 및 배송

집중력

from Human plasma; ≥2700 NIH U/mg protein; Pre-lyophilization Protein Concentration: See COA

재구성

We suggest hydrating the protein with a good quality water to the original volume (See COA). After hydration aliquot into a useful (one time use) size and freeze at -80℃.

보관 조건

Store at 2-8°C

배송

Wet ice

안정성 및 스토리지

Store at 2-8℃ long term. Upon reconstitution, it is recommended to aliquot and freeze at -80℃.