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· · COA & SDS 모든 제품에 대한 사용 가능 · 주식 상품에 대한 같은 날 배송 아카데신 - 몰리건드™, ≥98% , AMP-activated protein kinase, AMPK activator, CAS No.2627-69-2, AMP-activated protein kinase, AMPK activator
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98% Synonyms
MLS004774120 | 5-Amino-1-beta-D-ribofuranosylimidazole-4-carboxamide | 1H-Imidazole-4-carboxamide, 5-amino-1-.beta.-D-ribofuranosyl- | 53IEF47846 | 5-Amino-4-imidazolecarboxamide Riboside | ACADESINE [MI] | GP-1-110 | SCHEMBL219336 | SRI-4077_04 | Acadesi
Shipped In
아이스 박스 + 아이스 패드
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Why this grade 몰리건드™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping 20°C에서 보관 Ships 아이스 박스 + 아이스 패드 Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 2 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
개요 아카데신은 AMPK 및 AMPK 키나아제에 대한 AMP의 자극 효과를 모방하는 ZMP의 축적을 초래합니다.
Specifications 동의어
MLS004774120 | 5-Amino-1-beta-D-ribofuranosylimidazole-4-carboxamide | 1H-Imidazole-4-carboxamide, 5-amino-1-.beta.-D-ribofuranosyl- | 53IEF47846 | 5-Amino-4-imidazolecarboxamide Riboside | ACADESINE [MI] | GP-1-110 | SCHEMBL219336 | SRI-4077_04 | Acadesi
생화학 및 생리적 메커니즘
AICAR(AICA-리보사이드)는 PPAR&알파의 전사와 PPAR&알파의 상호 작용을 강력하게 억제합니다. 지방 세포 연구에서 이소프레날린에 의해 유도된 지방 분해를 길항하는 것으로 나타났으며 키나아제 캐스케이드 연구에 사용하도록 제안되었습니다. A
작동 메커니즘
AMP-activated protein kinase, AMPK activator
참고
가능하면 당일에 용액을 준비하여 사용하는 것이 좋습니다. 그러나 미리 원액을 만들어야 하는 경우에는 -20°C에서 단단히 밀봉된 바이알에 소량씩 보관하는 것이 좋습니다. 일반적으로 최대 한 달 동안 사용할 수 있습니다. 사용하기 전에 바이알을 개봉하기 전에 제품을 실온에서 1시간 이상 평형화할 것을 권장합니다. 용해도, 사용법 및 취급에 대한 추가 정보가 필요하신가요? 자주 묻는 질문(FAQ) 페이지에서 자세한 내용을 확인하세요.
제품 특성 이름과 식별자 Pubchem Sid Url
https://pubchem.ncbi.nlm.nih.gov/substance/488182399
정식 스마일
C1=NC(=C(N1C2C(C(C(O2)CO)O)O)N)C(=O)N
IUPAC Name
5-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]imidazole-4-carboxamide
InChIKey
RTRQQBHATOEIAF-UUOKFMHZSA-N
INCHI
1S/C9H14N4O5/c10-7-4(8(11)17)12-2-13(7)9-6(16)5(15)3(1-14)18-9/h2-3,5-6,9,14-16H,1,10H2,(H2,11,17)/t3-,5-,6-,9-/m1/s1
이성체 SMILES
C1=NC(=C(N1[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)N)C(=O)N
Reaxys-RN_link_address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=623893&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Nucleosides, nucleotides, and analogues 분류 Imidazole ribonucleosides and ribonucleotides Subclass Not available Intermediate Tree Nodes Not available Direct Parent Imidazole ribonucleosides and ribonucleotides Alternative Parents Glycosylamines Pentoses N-substituted imidazoles Aminoimidazoles Tetrahydrofurans Heteroaromatic compounds Secondary alcohols Oxacyclic compounds Carboximidic acids Azacyclic compounds Primary amines Primary alcohols Organopnictogen compounds Hydrocarbon derivatives Molecular Framework Aromatic heteromonocyclic compounds Substituents Imidazole ribonucleoside - Glycosyl compound - N-glycosyl compound - Pentose monosaccharide - Aminoimidazole - Monosaccharide - N-substituted imidazole - Azole - Heteroaromatic compound - Imidazole - Tetrahydrofuran - Secondary alcohol - Carboximidic acid - Carboximidic acid derivative - Oxacycle - Azacycle - Organoheterocyclic compound - Organic nitrogen compound - Hydrocarbon derivative - Organopnictogen compound - Amine - Alcohol - Organic oxygen compound - Primary amine - Organonitrogen compound - Organooxygen compound - Primary alcohol - Aromatic heteromonocyclic compound 설명 This compound belongs to the class of organic compounds known as imidazole ribonucleosides and ribonucleotides. These are organic compounds in which the C-1 of a ribosyl moiety is N-linked to an imidazole ring. Nucleotides have a phosphate group linked to the C5 carbon of the ribose (or deoxyribose) moiety. This class does not contain benzimidazole nucleosides and nucleotides. External Descriptors nucleoside analogue - aminoimidazole - 1-ribosylimidazolecarboxamide Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D 구조 관련 대상(인간) 관련 대상(비인간) 작용 메커니즘 인증서(CoA, COO, BSE/TSE 및 분석 차트) 화학 및 물리적 특성 용해성 Soluble in water (9 mg/ml), and DMSO (75 mM). 감도 Moisture sensitive 분자량 258.230 g/mol XLogP3 -2.200 Hydrogen Bond Donor Count 5 Hydrogen Bond Acceptor Count 7 Rotatable Bond Count 3 Exact Mass 258.096 Da Monoisotopic Mass 258.096 Da Topological Polar Surface Area 157.000 Ų Heavy Atom Count 18 Formal Charge 0 Complexity 330.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 4 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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