Acridine Orange base - ≥75% , CAS No.494-38-2

CAS: 494-38-2 Cat. No.: A121748 분자식: C₁₇H₁₉N₃ 분자량: 265.35

등급 & 순도 ≥75%

Synonyms

F30N4O6XVV | Oranz akridinova | 2,8-Bisdimethylaminoacridine | C.I. Solvent Orange 15 | C.I. 46005B | N,N,N(sup 1),N(sup 1)-Tetramethylacridinediamine | [6-(dimethylamino)acridin-3-yl]-dimethyl-amine | F19170 | NSC 194350 | 4-22-00-05490 (Beilstein Handbo

Storage

Room temperature

Shipped In

Normal

개요

When bound to DNA, it emits green fluorescence (Em=525 nm) and when bound to RNA, it emits red fluorescence (Em=~650 nm).
A fluorescent nucleic acid binding dye which interacts with both DNA and RNA.

사양

동의어

F30N4O6XVV | Oranz akridinova | 2,8-Bisdimethylaminoacridine | C.I. Solvent Orange 15 | C.I. 46005B | N,N,N(sup 1),N(sup 1)-Tetramethylacridinediamine | [6-(dimethylamino)acridin-3-yl]-dimethyl-amine | F19170 | NSC 194350 | 4-22-00-05490 (Beilstein Handbo

사양 및 순도

≥75%

보관 조건

Room temperature

배송

Normal

순수함

≥75%

이름과 식별자

Pubchem Sid

488183564

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/488183564

정식 스마일

CN(C)C1=CC2=C(C=C1)C=C3C=CC(=CC3=N2)N(C)C

IUPAC Name

3-N,3-N,6-N,6-N-tetramethylacridine-3,6-diamine

InChIKey

DPKHZNPWBDQZCN-UHFFFAOYSA-N

INCHI

1S/C17H19N3/c1-19(2)14-7-5-12-9-13-6-8-15(20(3)4)11-17(13)18-16(12)10-14/h5-11H,1-4H3

이성체 SMILES

CN(C)C1=CC2=C(C=C1)C=C3C=CC(=CC3=N2)N(C)C

WGK 독일

3

RTECS

AR7600000

분자량

265.35

Reaxy-Rn

20916

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=20916&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • 분류 Quinolines and derivatives
      • Subclass Benzoquinolines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• 분류: Quinolines and derivatives
• Subclass: Benzoquinolines
• Intermediate Tree Nodes: Not available
• Direct Parent: Acridines
• Alternative Parents: Aminoquinolines and derivatives Dialkylarylamines Pyridines and derivatives Benzenoids Heteroaromatic compounds Azacyclic compounds Organopnictogen compounds Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Acridine - Aminoquinoline - Dialkylarylamine - Tertiary aliphatic/aromatic amine - Benzenoid - Pyridine - Heteroaromatic compound - Tertiary amine - Azacycle - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organonitrogen compound - Amine - Aromatic heteropolycyclic compound
• 설명: This compound belongs to the class of organic compounds known as acridines. These are organic compounds containing the acridine moiety, a linear tricyclic heterocycle which consists of two benzene rings joined by a pyridine ring.
• External Descriptors: aminoacridines - tertiary amino compound - aromatic amine

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

관련 대상(인간)

APP Tclin Amyloid-beta A4 protein (1 Activities)

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APP Tclin Amyloid-beta A4 protein (8510 Activities)

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TERT Tchem Telomerase reverse transcriptase (2428 Activities)

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A498 (42825 Activities)

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CCRF-CEM (65223 Activities)

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DU-145 (51482 Activities)

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HT-29 (80576 Activities)

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K562 (73714 Activities)

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KM12 (47707 Activities)

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M14 (47487 Activities)

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MCF7 (126967 Activities)

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MOLT-4 (49676 Activities)

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OVCAR-3 (48710 Activities)

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OVCAR-4 (44535 Activities)

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OVCAR-8 (47708 Activities)

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PC-3 (62116 Activities)

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RPMI-8226 (44974 Activities)

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RXF 393 (41971 Activities)

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SF-295 (48000 Activities)

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SK-MEL-2 (46422 Activities)

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SK-MEL-28 (48833 Activities)

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SK-MEL-5 (47095 Activities)

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SK-OV-3 (52876 Activities)

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U-251 (51189 Activities)

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UACC-257 (46019 Activities)

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UACC-62 (47335 Activities)

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UO-31 (46270 Activities)

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786-0 (47912 Activities)

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A549 (127892 Activities)

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NCI/ADR-RES (33767 Activities)

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HCC 2998 (41480 Activities)

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SF-268 (49410 Activities)

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관련 대상(비인간)

pol Human immunodeficiency virus type 1 reverse transcriptase (18245 Activities)

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Pasteurella multocida (1166 Activities)

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Acinetobacter baumannii (41033 Activities)

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Rattus norvegicus (775804 Activities)

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작용 메커니즘

화학 및 물리적 특성

• 녹는점(°C): 165°C(dec.)(lit.)
• 분자량: 265.350 g/mol
• XLogP3: 3.400
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 265.158 Da
• Monoisotopic Mass: 265.158 Da
• Topological Polar Surface Area: 19.400 Ų
• Heavy Atom Count: 20
• Formal Charge: 0
• Complexity: 298.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

자주 묻는 질문

What is the purity of this product?

This product is supplied at ≥75% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at room temperature.

How is this product shipped?

This product ships under standard ambient conditions. No temperature-controlled packaging is required.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 494-38-2, the molecular formula is C17H19N3, and the molecular weight is 265.35 g/mol. InChIKey DPKHZNPWBDQZCN-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.