ACY-957 - Moligand™, ≥98% , CAS No.1609389-52-7

CAS: 1609389-52-7 Cat. No.: A650992 분자식: C₂₄H₂₃N₅OS 분자량: 429.54

GRADE & PURITY Moligand™, ≥98%

Synonyms

HDAC Inhibitor C001 | N-(2-Amino-5-(thiophen-2-yl)phenyl)-2-(piperazin-1-yl)quinoline-6-carboxamide

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

개요

ACY-957 is an orally active and selective inhibitor of HDAC1 and HDAC2 , with IC 50 s of 7 nM, 18 nM, and 1300 nM against HDAC1/2/3, respectively, and shows no inhibition on HDAC4/5/6/7/8/9

In Vitro

ACY-957 is a selective inhibitor of HDAC1 and HDAC2, with IC 50 s of 7 nM, 18 nM, and 1300 nM against HDAC1/2/3, respectively, and shows no inhibition on HDAC4/5/6/7/8/9. ACY-957 has an IC 50 of 304 nM for HDAC2 in primary hematopoietic progenitors. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:HDAC1 7 nM (IC 50 ) HDAC2 18 nM (IC 50 ) HDAC3 1300 nM (IC 50 )

Specifications

동의어

HDAC Inhibitor C001 | N-(2-Amino-5-(thiophen-2-yl)phenyl)-2-(piperazin-1-yl)quinoline-6-carboxamide

사양 및 순도

Moligand™, ≥98%

생화학 및 생리적 메커니즘

ACY-957 is an selective inhibitor of HDAC1 and HDAC2, with IC50s of 7 nM, 18 nM, and 1300 nM against HDAC1/2/3, respectively, and shows no inhibition on HDAC4/5/6/7/8/9.

보관 조건

Store at -20°C

배송

Ice chest + Ice pads

이 제품은 콜드 체인 배송이 필요합니다.지상 및 기타 경제 서비스는 사용할 수 없습니다.

등급

Moligand™

작업 유형

INHIBITOR

순수함

≥98%

이름과 식별자

• 분자량: 429.54

화학 및 물리적 특성

• 용해성: DMSO : 83.33 mg/mL (194.00 mM; Need ultrasonic)