ACY-957 - 10mM in DMSO , CAS No.1609389-52-7

CAS: 1609389-52-7 Cat. No.: A656485 분자식: C₂₄H₂₃N₅OS 분자량: 429.54

GRADE & PURITY 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

개요

ACY-957 is an orally active and selective inhibitor of HDAC1 and HDAC2 , with IC 50 s of 7 nM, 18 nM, and 1300 nM against HDAC1/2/3, respectively, and shows no inhibition on HDAC4/5/6/7/8/9

In Vitro

ACY-957 is a selective inhibitor of HDAC1 and HDAC2, with IC 50 s of 7 nM, 18 nM, and 1300 nM against HDAC1/2/3, respectively, and shows no inhibition on HDAC4/5/6/7/8/9. ACY-957 has an IC 50 of 304 nM for HDAC2 in primary hematopoietic progenitors. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:HDAC1 7 nM (IC 50 ) HDAC2 18 nM (IC 50 ) HDAC3 1300 nM (IC 50 )

Specifications

사양 및 순도

10mM in DMSO

생화학 및 생리적 메커니즘

ACY-957 is an orally active and selective inhibitor of HDAC1 and HDAC2 , with IC 50 s of 7 nM, 18 nM, and 1300 nM against HDAC1/2/3, respectively, and shows no inhibition on HDAC4/5/6/7/8/9.

보관 조건

Store at -80°C

배송

Dry ice packs + Cold packs

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작업 유형

INHIBITOR

이름과 식별자

• 분자량: 429.54