Name: Adomeglivant - Moligand™, ≥98% , Antagonist of glukagon receptor, CAS No.1488363-78-5, Antagonist of glukagon receptor
SKU: A412451
Availability: InStock

Adomeglivant - Moligand™, ≥98% , Antagonist of glukagon receptor, CAS No.1488363-78-5, Antagonist of glukagon receptor

CAS: 1488363-78-5 Cat. No.: A412451 분자식: C₃₂H₃₆F₃NO₄ 분자량: 555.63

Skip to the end of the images gallery

Adomeglivant - Moligand™, ≥98% CAS No(1488363-78-5) by Aladdin Scientific

Skip to the beginning of the images gallery

주문 가능

GRADE & PURITY Moligand™ ? ≥98%

Synonyms

F85410 | AKOS040741049 | FASLTMSUPQDLIB-MHZLTWQESA-N | A858152 | ADOMEGLIVANT [WHO-DD] | .BETA.-ALANINE, N-(4-((1S)-1-((4'-(1,1-DIMETHYLETHYL)-2,6-DIMETHYL(1,1'-BIPHENYL)-4-YL)OXY)-4,4,4-TRIFLUOROBUTYL)BENZOYL)- | MS-30128 | UNII-74Z5ZL2KVG | 1488363-78-5

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

개요 Specifications 제품 특성 이름과 식별자 Documentation Advanced Data Taxonomic Classification 3D 구조 관련 대상(인간) 관련 대상(비인간) 작용 메커니즘 인증서(CoA, COO, BSE/TSE 및 분석 차트) 화학 및 물리적 특성 솔루션 계산기 리뷰

🧪

Why this grade

Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

개요

Information

Adomeglivant Adomeglivant (LY2409021) is a potent and selective antagonist of glukagon receptor that is used as a chronic treatment for type 2 diabetes.

Adomeglivant (LY2409021) is a potent, selective glukagon receptor (GluR) allosteric antagonist. Adomeglivant is widely used in the research for type 2 diabetes mellitus.

Targets

Glukagon Receptor

Specifications

동의어

사양 및 순도

Moligand™, ≥98%

생화학 및 생리적 메커니즘

Adomeglivant (LY2409021) is a potent and selective antagonist of glukagon receptor that is used as a chronic treatment for type 2 diabetes.

보관 조건

Store at -20°C

배송

Ice chest + Ice pads

이 제품은 콜드 체인 배송이 필요합니다.지상 및 기타 경제 서비스는 사용할 수 없습니다.

등급

Moligand™

작업 유형

ANTAGONIST

작동 메커니즘

Antagonist of glukagon receptor

순수함

≥98%

제품 특성

ALogP	7.839
hba_count	3
HBD 수	1
회전 가능한 결합	12

이름과 식별자

Pubchem Sid	488202541
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488202541
정식 스마일	CC1=CC(=CC(=C1C2=CC=C(C=C2)C(C)(C)C)C)OC(CCC(F)(F)F)C3=CC=C(C=C3)C(=O)NCCC(=O)O
IUPAC Name	3-[[4-[(1S)-1-[4-(4-tert-butylphenyl)-3,5-dimethylphenoxy]-4,4,4-trifluorobutyl]benzoyl]amino]propanoic acid
InChIKey	FASLTMSUPQDLIB-MHZLTWQESA-N
INCHI	1S/C32H36F3NO4/c1-20-18-26(19-21(2)29(20)23-10-12-25(13-11-23)31(3,4)5)40-27(14-16-32(33,34)35)22-6-8-24(9-7-22)30(39)36-17-15-28(37)38/h6-13,18-19,27H,14-17H2,1-5H3,(H,36,39)(H,37,38)/t27-/m0/s1
이성체 SMILES	CC1=CC(=CC(=C1C2=CC=C(C=C2)C(C)(C)C)C)O[C@@H](CCC(F)(F)F)C3=CC=C(C=C3)C(=O)NCCC(=O)O
대체 CAS	872260-20-3,1488363-78-5
MeSH 용어	(+)-adomeglivant;(+-)-adomeglivant;(-)-adomeglivant;3-(4-((1R)-1-((4'-tert-butyl-2,6-dimethylbiphenyl-4-yl)oxy)-4,4,4-trifluorobutyl)benzamido)propanoic acid;3-(4-((1S)-1-((4'-tert-butyl-2,6-dimethylbiphenyl-4-yl)oxy)-4,4,4-trifluorobutyl)benzamido)propan
분자량	555.63
Reaxy-Rn	12479521
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=12479521&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Benzenoids
  - 분류 Benzene and substituted derivatives
    - Subclass Biphenyls and derivatives

Kingdom	Organic compounds
Superclass	Benzenoids
분류	Benzene and substituted derivatives
Subclass	Biphenyls and derivatives
Intermediate Tree Nodes	Not available
Direct Parent	Biphenyls and derivatives
Alternative Parents	Beta amino acids and derivatives Benzamides Phenylpropanes m-Xylenes Benzoyl derivatives Phenol ethers Phenoxy compounds Alkyl aryl ethers Secondary carboxylic acid amides Monocarboxylic acids and derivatives Carboxylic acids Organic oxides Hydrocarbon derivatives Carbonyl compounds Organofluorides Organonitrogen compounds Alkyl fluorides
Molecular Framework	Aromatic homomonocyclic compounds
Substituents	Biphenyl - Beta amino acid or derivatives - Benzamide - Benzoic acid or derivatives - Phenylpropane - Phenoxy compound - M-xylene - Xylene - Benzoyl - Phenol ether - Alkyl aryl ether - Secondary carboxylic acid amide - Carboxamide group - Monocarboxylic acid or derivatives - Ether - Carboxylic acid - Carboxylic acid derivative - Organohalogen compound - Alkyl fluoride - Carbonyl group - Organooxygen compound - Organic nitrogen compound - Hydrocarbon derivative - Organic oxide - Organic oxygen compound - Alkyl halide - Organofluoride - Organonitrogen compound - Aromatic homomonocyclic compound
설명	This compound belongs to the class of organic compounds known as biphenyls and derivatives. These are organic compounds containing to benzene rings linked together by a C-C bond.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

3D 구조

Molarity Calculator

Determine the necessary mass, volume, or concentration for preparing a solution.

Dilution Calculator

Determine the dilution needed to prepare a stock solution.

Reconstitution Calculator

리뷰

Need help choosing the grade?

Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

View Moligand™ grade guide →

Bulk & Custom Packaging Need larger quantities or custom specifications? Contact our team for a tailored quote.

Lot Number	Certificate Type	날짜	항목
C2321105	Certificate of Analysis	Feb 08, 2023	A412451
C2321111	Certificate of Analysis	Feb 08, 2023	A412451
C2321121	Certificate of Analysis	Feb 08, 2023	A412451
C2321191	Certificate of Analysis	Feb 08, 2023	A412451
C2321227	Certificate of Analysis	Feb 08, 2023	A412451
C2321228	Certificate of Analysis	Feb 08, 2023	A412451
C2321238	Certificate of Analysis	Feb 08, 2023	A412451
C2321297	Certificate of Analysis	Feb 08, 2023	A412451
C2321302	Certificate of Analysis	Feb 08, 2023	A412451
C2321351	Certificate of Analysis	Feb 08, 2023	A412451

용해성	Solubility (25°C) In vitro DMSO: 100 mg/mL (179.97 mM); Ethanol: 100 mg/mL (179.97 mM); Water: Insoluble;
DMSO(mg/mL) 최대 용해도	100
DMSO(mM) 최대 용해도	179.975883231647
물(mg/mL) 최대 용해도	＜1
분자량	555.600 g/mol
XLogP3	8.100
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	11
Exact Mass	555.26 Da
Monoisotopic Mass	555.26 Da
Topological Polar Surface Area	75.600 Å²
Heavy Atom Count	40
Formal Charge	0
Complexity	798.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1