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Aladdin™ Coupling Catalyst
주문 가능
Storage
Store at 2-8°C
Shipped In
Wet ice
이 등급을 선택하는 이유
최소한의 기준선 간섭이 필요한 민감한 크로마토그래피 및 분석 워크플로우용.
보관 및 배송
Store at 2-8°C Wet ice 출고. 정확한 사양은 로트별 COA를 확인하세요.
품질 문서
SDS, COA, 데이터시트, 사양서를 다운로드할 수 있습니다. 로트별 COA는 로트 번호 조회를 통해 확인할 수 있습니다.
문헌적 근거
크로마토그래피, 유기 합성 및 교차 커플링 반응 분야의 동료 심사 논문 0편에서 인용되었습니다.
개요
Product introduction：
Coupling Catalyst decreases reaction times and increases aldehyde-hydrazide coupling efficiency, resulting in greater than 90% coupling of glycoproteins in 4 hours.
Features of the GlycoLink Coupling Catalyst:
• Optimized—catalyzes aldehyde-hydrazide and aldehyde-alkoxyamine conjugation reaction
• Efficient—maximizes coupling efficiency and decreases required coupling reaction incubation time
• Gentle—does not interfere with protein function and is easily removed by desalting or dialysis
The GlycoLink Coupling Catalyst is a two component kit composed of aniline and sodium acetate buffer. The catalyst accelerates the coupling rate of hydrazide and alkoxyamine moieties with reactive aldehydes that have been generated by periodate-oxidation of cis-diols in glycoproteins. The GlycoLink Coupling Catalyst increases the coupling efficiency of these reactions, decreasing the molar excess amounts of labeling reagents that are required for conjugation reactions. The catalyst is also useful for increasing the binding efficiency of oxidized glycoproteins or other carbohydrate-containing molecules to hydrazide resins.
Applications
• Labeling aldehyde-containing molecules with alkoxyamine-biotins
• Labeling aldehyde-containing molecules with hydrazide-biotins
• Increase coupling efficiency of aldehyde-containing molecules to hydrazide resin
Producing reactive aldehydes via sodium meta-periodate oxidation of cis-diols in glycoproteins is a useful technique for variety of protein labeling and detection methods. The GlycoLink Coupling Catalyst (aniline) increases the efficiency of these reactions by acting as a nucleophilic catalyst that accelerates bond formation through a Schiff base intermediate. The catalyst also reduces the amount (molar excess) of hydrazide or alkoxyamine required in labeling reactions, thereby eliminating the need for DMSO to solubilize high concentrations of labeling reagent.
More Product Data
•Improved immobilization and conjugation of glycoproteins
Features of the GlycoLink Coupling Catalyst:
• Optimized—catalyzes aldehyde-hydrazide and aldehyde-alkoxyamine conjugation reaction
• Efficient—maximizes coupling efficiency and decreases required coupling reaction incubation time
• Gentle—does not interfere with protein function and is easily removed by desalting or dialysis
The GlycoLink Coupling Catalyst is a two component kit composed of aniline and sodium acetate buffer. The catalyst accelerates the coupling rate of hydrazide and alkoxyamine moieties with reactive aldehydes that have been generated by periodate-oxidation of cis-diols in glycoproteins. The GlycoLink Coupling Catalyst increases the coupling efficiency of these reactions, decreasing the molar excess amounts of labeling reagents that are required for conjugation reactions. The catalyst is also useful for increasing the binding efficiency of oxidized glycoproteins or other carbohydrate-containing molecules to hydrazide resins.
Applications
• Labeling aldehyde-containing molecules with alkoxyamine-biotins
• Labeling aldehyde-containing molecules with hydrazide-biotins
• Increase coupling efficiency of aldehyde-containing molecules to hydrazide resin
Producing reactive aldehydes via sodium meta-periodate oxidation of cis-diols in glycoproteins is a useful technique for variety of protein labeling and detection methods. The GlycoLink Coupling Catalyst (aniline) increases the efficiency of these reactions by acting as a nucleophilic catalyst that accelerates bond formation through a Schiff base intermediate. The catalyst also reduces the amount (molar excess) of hydrazide or alkoxyamine required in labeling reactions, thereby eliminating the need for DMSO to solubilize high concentrations of labeling reagent.
More Product Data
•Improved immobilization and conjugation of glycoproteins
• Form:Liquid
사양
보관 조건
Store at 2-8°C
배송
Wet ice
이 제품은 콜드 체인 배송이 필요합니다.지상 및 기타 경제 서비스는 사용할 수 없습니다.
문서
📋 안전 데이터 시트(SDS)
위험성, 취급, 보관 및 규제 준수를 포괄하는 종합 문서.
<<<<<<< HEAD SDS 다운로드 → ======= SDS 다운로드 → >>>>>>> release248-p3고급 데이터
인증서(CoA, COO, BSE/TSE 및 분석 차트)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
솔루션 계산기
리뷰
고객 리뷰
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