Amiloride - Moligand™, 10 mM in DMSO , CAS No.2609-46-3

CAS: 2609-46-3 Cat. No.: A1499343 분자식: C₆H₈ClN₇O 분자량: 229.63 Beilstein Registry Number: 616612 EC 번호: 220-024-7

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

개요

Amiloride (MK-870) is an inhibitor of both epithelial sodium channel ( ENaC) and urokinase-type plasminogen activator receptor ( uTPA). Amiloride is a blocker of polycystin-2 (PC2; TRPP2) channel.

Specifications

사양 및 순도

Moligand™, 10 mM in DMSO

보관 조건

Store at -80°C

배송

Dry ice packs + Cold packs

이 제품은 콜드 체인 배송이 필요합니다.지상 및 기타 경제 서비스는 사용할 수 없습니다.

등급

Moligand™

제품 특성

• pKa: pKa: 7.81 (Predicted), pKa: 3.78 (Predicted)
• Ki 데이터: uPA: Ki= 2.51 μM (human); Adenosine A2A-R: Ki= 3.28 μM (human); Solute carrier family 22 member 2: Ki= 4.7 μM (rat); Solute carrier family 22 member 1: Ki= 6.9 μM (rat); Amine oxidase, copper containing: Ki= 10 μM (rat)

이름과 식별자

• 이성체 SMILES: C1(=C(N=C(C(=N1)Cl)N)N)C(=O)N=C(N)N
• 대체 CAS: 2016-88-8;17440-83-4
• 분자량: 229.63
• Beilstein: 616612

화학 및 물리적 특성

• 굴절률: n20D1.89 (Predicted)
• 끓는점(°C): ~557.9° C at 760 mmHg (Predicted)
• 녹는점(°C): 185.21° C (Predicted)

참고 문헌

1. Ruoning Wang, Qifan Liang, Xinru Zhang, Zhenning Di, Xiaohong Wang, Liuqing Di.  (2022)  Tumor-derived exosomes reversing TMZ resistance by synergistic drug delivery for glioma-targeting treatment.  COLLOIDS AND SURFACES B-BIOINTERFACES,      [PMID:35487070] [10.1016/j.colsurfb.2022.112505]

자주 묻는 질문

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 2609-46-3, the molecular formula is C6H8ClN7O, and the molecular weight is 229.63 g/mol.