Asundexian - Moligand™, 10mM in DMSO , CAS No.2064121-65-7

CAS: 2064121-65-7 Cat. No.: A654979 분자식: C₂₆H₂₁ClF₄N₆O₄ 분자량: 592.93 EC 번호: 963-875-6 PubChem CID: 135206011

GRADE & PURITY Moligand™, 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

개요

Asundexian (BAY 2433334) is an orally active coagulation factor Xia (FXIa) inhibitor. Asundexian binds directly, potently, and reversibly to the active site of FXIa and thereby inhibits its activity. Asundexian inhibits human FXIa in buffer with an IC 50 of 1 nM.

In Vivo

Asundexian displays potent anticoagulant activity in vitro in human and rabbit plasma and antithrombotic efficacy in vivo in a rabbit arterial thrombosis model . MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Specifications

사양 및 순도

Moligand™, 10mM in DMSO

생화학 및 생리적 메커니즘

Asundexian (BAY 2433334) is an orally active coagulation factor Xia (FXIa) inhibitor. Asundexian binds directly, potently, and reversibly to the active site of FXIa and thereby inhibits its activity. Asundexian inhibits human FXIa in buffer with an IC 50

보관 조건

Store at -80°C

배송

Dry ice packs + Cold packs

이 제품은 콜드 체인 배송이 필요합니다.지상 및 기타 경제 서비스는 사용할 수 없습니다.

등급

Moligand™

작업 유형

INHIBITOR

이름과 식별자

• 이성체 SMILES: CC[C@@H](C(=O)NC1=CC(=C(C=C1)C(=O)N)F)N2C=C(C(=CC2=O)C3=C(C=CC(=C3)Cl)N4C=C(N=N4)C(F)(F)F)OC
• PubChem CID: 135206011
• 분자량: 592.93