AX-024 HCl - 10mM in DMSO , CAS No.1704801-24-0

CAS: 1704801-24-0 Cat. No.: A422102 분자식: C₂₁H₂₃ClFNO₂ 분자량: 375.86

등급 & 순도 10mM in DMSO

Synonyms

AX-024 hydrochloride | 1-​[[4-​(4-​fluorophenyl)​-​6-​methoxy-​2H-​1-​benzopyran-​3-​yl]​methyl]​-​,hydrochloride (1:1)

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

개요

Information

AX-024 HCl AX-024 HCl blocks the interaction of the CD3ε PRS with SH3.1(Nck). AX-024 HCl also inhibits IL-6 , TNF-α , IFN-γ , IL-10 and IL-17A .

사양

동의어

AX-024 hydrochloride | 1-​[[4-​(4-​fluorophenyl)​-​6-​methoxy-​2H-​1-​benzopyran-​3-​yl]​methyl]​-​,hydrochloride (1:1)

사양 및 순도

10mM in DMSO

생화학 및 생리적 메커니즘

AX-024 HCl blocks the interaction of the CD3ε PRS with SH3.1(Nck). AX-024 HCl also inhibits IL-6, TNF-α, IFN-γ, IL-10 and IL-17A.

보관 조건

Store at -80°C

배송

Dry ice packs + Cold packs

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작업 유형

INHIBITOR

제품 특성

ALogP

4.579

hba_count

2

회전 가능한 결합

4

이름과 식별자

Pubchem Sid

528763182

정식 스마일

COC1=CC2=C(C=C1)OCC(=C2C3=CC=C(C=C3)F)CN4CCCC4.Cl

IUPAC Name

1-[[4-(4-fluorophenyl)-6-methoxy-2H-chromen-3-yl]methyl]pyrrolidine;hydrochloride

InChIKey

DGBCIMPGYRVTPD-UHFFFAOYSA-N

INCHI

1S/C21H22FNO2.ClH/c1-24-18-8-9-20-19(12-18)21(15-4-6-17(22)7-5-15)16(14-25-20)13-23-10-2-3-11-23;/h4-9,12H,2-3,10-11,13-14H2,1H3;1H

대체 CAS

1370544-73-2

분자량

375.86

Reaxy-Rn

30387316

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=30387316&ln=

화학 및 물리적 특성

• DMSO(mg/mL) 최대 용해도: 75
• DMSO(mM) 최대 용해도: 199.542382802107
• 물(mg/mL) 최대 용해도: 4
• 물(mM) 최대 용해도: 10.6422604161124
• 분자량: 375.900 g/mol
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 375.14 Da
• Monoisotopic Mass: 375.14 Da
• Topological Polar Surface Area: 21.700 Ų
• Heavy Atom Count: 26
• Formal Charge: 0
• Complexity: 480.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3