Determine the necessary mass, volume, or concentration for preparing a solution.
10mM in DMSO 최소한의 기준선 간섭이 필요한 민감한 크로마토그래피 및 분석 워크플로우용.
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크로마토그래피, 유기 합성 및 교차 커플링 반응 분야의 동료 심사 논문 0편에서 인용되었습니다.
Information
Azacyclonol (MER 17, MDL 4829), also known as γ-pipradol, is a drug used to diminish hallucinations in psychotic individuals.
In vitro
The formation of Azacyclonol in human intestinal microsomes is linear with respect to time up to 60 min. The rates of formation of Azacyclonol increases linearly with microsomal protein concentration up to 2 mg/mL. The apparent Km and Vmax values of Azacyclonol are 0.82 μM and 60 pmol/min/mg protein in microsomes from human liver. The formation of Azacyclonol and terfenadine alcohol from terfenadine is confirmed to be catalyzed predominantly by CYP3A(4) isozyme, and the ratio of the rate of terfenadine alcohol formation to that of Azacyclonol is 3:1. The amount of Azacyclonol eliminated renally increases on average 2-fold after rifampin dosing.
In vivo
Azacyclonol (i.v.) impairs the response of the nictitating membrane to both post- and preganglionic stimulation. The activity of Azacyclonol in depressing transmission through the cat superior ceivical ganglion is 6.63%.
Cell Data
cell lines:HCT116 cells and HCT116 TP53-/- cells
Concentrations:
Incubation Time:
Powder Purity:≥99%
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<<<<<<< HEAD SDS 다운로드 → ======= SDS 다운로드 → >>>>>>> release248-p3Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | 날짜 | 항목 |
|---|---|---|---|
| Certificate of Analysis | Jun 04, 2026 | A408482 |
| 녹는점(°C) | 163 °C |
|---|