Azido-PEG2-CH2COOH - ≥97% , CAS No.882518-90-3

CAS: 882518-90-3 Cat. No.: A412701 분자식: C₆H₁₁N₃O₄ 분자량: 189.17

GRADE & PURITY ≥97%

Synonyms

Azide-PEG2-CH2COOH | Azido-PEG2-CH2COOH | 2-[2-(2-Azidoethoxy)ethoxy]acetic acid | N-(2-(2-(2-azidoethoxy)ethoxy))acetic acid | Acetic acid, [2-(2-azidoethoxy)ethoxy]-3,6-Dioxa-8-azidooctanoic acid

Storage

Protected from light,Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Application

Antibody Drug Conjugates(ADC), Drug Delivery, Surface Modification, PEGylation of Protein, Peptide & Oligo

개요

Azido-PEG2-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Azido-PEG2-CH2COOH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

Specifications

동의어

Azide-PEG2-CH2COOH | Azido-PEG2-CH2COOH | 2-[2-(2-Azidoethoxy)ethoxy]acetic acid | N-(2-(2-(2-azidoethoxy)ethoxy))acetic acid | Acetic acid, [2-(2-azidoethoxy)ethoxy]-3,6-Dioxa-8-azidooctanoic acid

사양 및 순도

≥97%

생화학 및 생리적 메커니즘

Azido-PEG2-CH2COOH is a PEG-based PROTAC linker that is applicable to the synthesis of PROTACs.

보관 조건

Protected from light,Store at -20°C,Argon charged

배송

Ice chest + Ice pads

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순수함

≥97%

이름과 식별자

Pubchem Sid

508812861

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/508812861

정식 스마일

C(COCCOCC(=O)O)N=[N+]=[N-]

IUPAC Name

2-[2-(2-azidoethoxy)ethoxy]acetic acid

InChIKey

OCIIYNXOTJRSHW-UHFFFAOYSA-N

INCHI

1S/C6H11N3O4/c7-9-8-1-2-12-3-4-13-5-6(10)11/h1-5H2,(H,10,11)

이성체 SMILES

C(COCCOCC(=O)O)N=[N+]=[N-]

분자량

189.17

Reaxy-Rn

11079311

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=11079311&ln=

화학 및 물리적 특성

• 용해성: Solubility (25°C) In vitro
• 감도: Moisture sensitive；Light sensitive
• 분자량: 189.170 g/mol
• XLogP3: 0.400
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 8
• Exact Mass: 189.075 Da
• Monoisotopic Mass: 189.075 Da
• Topological Polar Surface Area: 70.100 Ų
• Heavy Atom Count: 13
• Formal Charge: 0
• Complexity: 190.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1