BAY-805 - ≥99% , CAS No.2925481-88-3

CAS: 2925481-88-3 Cat. No.: B649535 분자식: C₂₄H₂₈F₃N₅O₂S 분자량: 507.57

GRADE & PURITY ≥99%

Storage

Store at 2-8°C,Protected from light,Desiccated

Shipped In

Wet ice

개요

BAY-805 is a selective inhibitor of ubiquitin-specific protease USP21 . BAY-805 has high selectivity for deubiquitinating enzyme (DUB) targets, kinases, proteases and other common target enzymes

In Vitro

BAY-805 inhibits the activity of hUSP21 HTRF and hUSP21 Ub-Rhod with IC 50 values of 6 nM and 2 nM, respectively. BAY-805 (10 µM) induces the NF-κB activation with an EC 50 value of 17 nM. BAY-805 (10 µM and 50 µM) significantly inhibits the activity of USP21 and also shows weak influence on USP22 and USP10. BAY-805 (0.0001-1000000 nM) selectively inhibits the activity of USP21. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:USP21

Specifications

사양 및 순도

≥99%

생화학 및 생리적 메커니즘

BAY-805 is a selective inhibitor of ubiquitin-specific protease USP21 . BAY-805 has high selectivity for deubiquitinating enzyme (DUB) targets, kinases, proteases and other common target enzymes.

보관 조건

Store at 2-8°C,Protected from light,Desiccated

배송

Wet ice

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작업 유형

INHIBITOR

순수함

≥99%

이름과 식별자

• 분자량: 507.57

화학 및 물리적 특성

• 용해성: DMSO : ≥ 200 mg/mL (394.03 mM)