Beclomethasone dipropionate - Moligand™, 10mM in DMSO , Glucocorticoid receptor agonist, CAS No.5534-09-8, Glucocorticoid receptor agonist

CAS: 5534-09-8 Cat. No.: B409241 분자식: C₂₈H₃₇ClO₇ 분자량: 521.04 EC 번호: 226-886-0

GRADE & PURITY Moligand™, 10mM in DMSO

Synonyms

Beclometasone dipropionate | 9α-Chloro-16β-methylprednisolone 17,21-dipropionate

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

개요

Information

Beclomethasone dipropionate Beclomethasone dipropionate is a potent glucocorticoid steroid used for the treatment of rhinitis and sinusitis.
In vitro

Beclomethasone dipropionate (BDP) is an anti-inflammatory corticosteroid available for the treatment of asthma and allergic rhinitis (AR). BDP is previously developed as aqueous nasal formulations for the treatment of AR. BDP is also available in dry nasal aerosol formulations as chlorofluoro carbon (CFC) metered-dose inhaler nasal sprays, but CFC-containing formulations have been withdrawn from the market and currently are not available.BDP hydrofluoroalkane (HFA) inhalation aerosol currently is available for patient use and indicated for the maintenance treatment of asthma as prophylactic therapy in patients 5 years of age and older.BDP HFA nasal aerosol, an intranasal aerosol formulation, has been developed recently for the treatment of AR.

In vivo

Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

동의어

Beclometasone dipropionate | 9α-Chloro-16β-methylprednisolone 17,21-dipropionate

사양 및 순도

Moligand™, 10mM in DMSO

생화학 및 생리적 메커니즘

Beclomethasone dipropionate is a potent glucocorticoid steroid used for the treatment of rhinitis and sinusitis.

보관 조건

Store at -80°C

배송

Dry ice packs + Cold packs

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등급

Moligand™

작업 유형

AGONIST

작동 메커니즘

Glucocorticoid receptor agonist

제품 특성

ALogP

3

이름과 식별자

이성체 SMILES

CCC(=O)OCC(=O)[C@]1([C@H](C[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2CCC4=CC(=O)C=C[C@@]43C)Cl)O)C)C)OC(=O)CC

RTECS

TU3805000

대체 CAS

66734-13-2

분자량

521.04

Reaxy-Rn

24731460

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=24731460&ln=

관련 대상(인간)

ADGRG3 Tchem Adhesion G protein-coupled receptor G3 (1 Activities)

Discover Target: ADGRG3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

화학 및 물리적 특성

• 녹는점(°C): 208-210°C