Befotertinib - ≥99% , CAS No.1835667-63-4

CAS: 1835667-63-4 Cat. No.: B651968 분자식: C₂₉H₃₂F₃N₇O₂ 분자량: 567.61 PubChem CID: 130412842

등급 & 순도 ≥99%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

개요

Befotertinib (D-0316) is the third-generation EGFR tyrosine kinase inhibitor. Befotertinib can be used for the research of EGFR T790M-positive non-small cell lung cancer (NSCLC)

Form:Solid

IC50& Target:EGFR tyrosine kinase

사양

사양 및 순도

≥99%

생화학 및 생리적 메커니즘

Befotertinib (D-0316) is the third-generation EGFR tyrosine kinase inhibitor. Befotertinib can be used for the research of EGFR T790M-positive non-small cell lung cancer (NSCLC).

보관 조건

Store at -20°C

배송

Ice chest + Ice pads

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작업 유형

INHIBITOR

순수함

≥99%

이름과 식별자

이성체 SMILES

CN(C)CCN(C)C1=CC(=C(C=C1NC(=O)C=C)NC2=NC=CC(=N2)C3=CN(C4=CC=CC=C43)CC(F)(F)F)OC

PubChem CID

130412842

분자량

567.61

화학 및 물리적 특성

• 용해성: DMSO : 50 mg/mL (88.09 mM; ultrasonic and warming and heat to 60°C)
• 분자량: 567.600 g/mol
• XLogP3: 4.800
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 11
• Exact Mass: 567.257 Da
• Monoisotopic Mass: 567.257 Da
• Topological Polar Surface Area: 87.600 Ų
• Heavy Atom Count: 41
• Formal Charge: 0
• Complexity: 863.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1