(+)-바이오틴 하이드라자이드 - ≥98% , CAS No.66640-86-6

CAS: 66640-86-6 Cat. No.: B122221 분자식: C₁₀H₁₈N₄O₂S 분자량: 258.34 Beilstein Registry Number: 28347 EC 번호: 613-970-0

GRADE & PURITY ≥98%

Synonyms

5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanehydrazide | 1H-Thieno(3,4-d)imidazole-4-pentanoic acid, hexahydro-2-oxo-, hydrazide, (3aS-(3aalpha,4beta,6aalpha))- | Biotin-NHNH2 | AS-74083 | 1H-Thieno[3,4-d]imidazole-4-pent

Storage

2-8°C에서 보관

Shipped In

젖은 얼음

개요

비오틴 히드라자이드는 당 단백질을 당 모티브로 비오틴화하는데 사용되는 비오틴화 시약으로, 비오틴 히드라자이드는 비오틴-공액 알긴산염을 제조하는 데 사용할 수 있으며 카르보디-이미드 교차 결합을 통해 PAAc에 공유 결합하는 데에도 사용할 수 있습니다.
표면 작용기, 항체, 렉틴, 당, 핵산 또는 유리 카르복실기 또는 케토기가 있는 분자와 같은 생물학적 활성 분자를 표지하기 위한 시약입니다. 일반적으로 히드라존 형성에 의해 탄수화물을 통해 당단백질에 결합하는 데 사용됩니다.

Specifications

동의어

5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanehydrazide | 1H-Thieno(3,4-d)imidazole-4-pentanoic acid, hexahydro-2-oxo-, hydrazide, (3aS-(3aalpha,4beta,6aalpha))- | Biotin-NHNH2 | AS-74083 | 1H-Thieno[3,4-d]imidazole-4-pent

사양 및 순도

≥98%

보관 조건

2-8°C에서 보관

배송

젖은 얼음

순수함

≥98%

이름과 식별자

Pubchem Sid

504755733

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/504755733

정식 스마일

C1C2C(C(S1)CCCCC(=O)NN)NC(=O)N2

IUPAC Name

5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanehydrazide

InChIKey

KOZWHQPRAOJMBN-ZKWXMUAHSA-N

INCHI

1S/C10H18N4O2S/c11-14-8(15)4-2-1-3-7-9-6(5-17-7)12-10(16)13-9/h6-7,9H,1-5,11H2,(H,14,15)(H2,12,13,16)/t6-,7-,9-/m0/s1

이성체 SMILES

C1[C@H]2[C@@H]([C@@H](S1)CCCCC(=O)NN)NC(=O)N2

WGK 독일

3

분자량

258.34

Beilstein

28347

Reaxy-Rn

260325

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=260325&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • 분류 Biotin and derivatives

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• 분류: Biotin and derivatives
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Biotin and derivatives
• Alternative Parents: Thienoimidazolidines Imidazolidinones Thiophenes Thiolanes Ureas Carboxylic acid hydrazides Dialkylthioethers Azacyclic compounds Organopnictogen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic heteropolycyclic compounds
• Substituents: Biotin_derivative - Thienoimidazolidine - Imidazolidinone - Imidazolidine - Thiolane - Thiophene - Carboxylic acid hydrazide - Carbonic acid derivative - Urea - Carboxylic acid derivative - Azacycle - Thioether - Dialkylthioether - Organonitrogen compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic oxygen compound - Organooxygen compound - Organic nitrogen compound - Carbonyl group - Aliphatic heteropolycyclic compound
• 설명: This compound belongs to the class of organic compounds known as biotin and derivatives. These are organic compounds containing a ureido (tetrahydroimidizalone) ring fused with a tetrahydrothiophene ring.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

작용 메커니즘

화학 및 물리적 특성

• 감도: Heat sensitive
• 녹는점(°C): 233 °C
• 분자량: 258.339 g/mol
• XLogP3: -0.700
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 258.115 Da
• Monoisotopic Mass: 258.115 Da
• Topological Polar Surface Area: 122.000 Ų
• Heavy Atom Count: 17
• Formal Charge: 0
• Complexity: 313.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 3
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1