Biotin-PEG3-azide - ≥98% , CAS No.875770-34-6

CAS: 875770-34-6 Cat. No.: B595159 분자식: C18H32N6SO5 분자량: 444.55
주문 가능
GRADE & PURITY ≥98%
Storage
Protected from light,Store at -20°C,Argon charged
Shipped In
Ice chest + Ice pads
★
Size
USA
독일 (EU)*
Price
Qty
100mg
B595159-100mg
주문제작 · 8~12주
US$139.90
250mg
B595159-250mg
주문제작 · 8~12주
US$279.90
500mg
B595159-500mg
주문제작 · 8~12주
US$449.90
1g
B595159-1g
주문제작 · 8~12주
US$699.90
Enter a quantity for the sizes you want to add.
🧪

Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Protected from light,Store at -20°C,Argon charged Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 8 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

개요

Biotin-PEG3-azide is PEG derivative containing a biotin group and an azide group. The azide group can react with either alkyne moiety in Cu(I)-catalyzed Click Chemistry reaction or DBCO moiety in copper-free Click Chemistry reaction to form a stable triazole linkage. The hydrophilic PEG spacer increases solubility in aqueous media of the molecules conjugated to the biotin compound. It also helps to minimize steric hindrance involved with the binding to avidin molecules.

Specifications

사양 및 순도
≥98%
보관 조건
Protected from light,Store at -20°C,Argon charged
배송
Ice chest + Ice pads
이 제품은 콜드 체인 배송이 필요합니다.지상 및 기타 경제 서비스는 사용할 수 없습니다.
순수함
≥98%
이름과 식별자
정식 스마일C1C2C(C(S1)CCCCC(=O)NCCOCCOCCOCCN=[N+]=[N-])NC(=O)N2
IUPAC Name5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-N-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]pentanamide
InChIKeyZWFOOMQCYIGZBE-ZOBUZTSGSA-N
INCHI1S/C18H32N6O5S/c19-24-21-6-8-28-10-12-29-11-9-27-7-5-20-16(25)4-2-1-3-15-17-14(13-30-15)22-18(26)23-17/h14-15,17H,1-13H2,(H,20,25)(H2,22,23,26)/t14-,15-,17-/m0/s1
이성체 SMILES C1[C@H]2[C@@H]([C@@H](S1)CCCCC(=O)NCCOCCOCCOCCN=[N+]=[N-])NC(=O)N2
분자량 444.55
Reaxy-Rn 19578611
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=19578611&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

3D 구조
상호 작용 화학 구조 모델





작용 메커니즘
인증서(CoA, COO, BSE/TSE 및 분석 차트)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
화학 및 물리적 특성
감도Light sensitive
녹는점(°C)110 °C
분자량444.600 g/mol
XLogP30.500
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count8
Rotatable Bond Count17
Exact Mass444.215 Da
Monoisotopic Mass444.215 Da
Topological Polar Surface Area138.000 Ų
Heavy Atom Count30
Formal Charge0
Complexity577.000
Isotope Atom Count0
Defined Atom Stereocenter Count3
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
자주 묻는 질문과 기사
Citations of This Product
참고 문헌
1. Jiang Yongpeng, Huang Jie, Tian Kai, Yi Xiao, Zheng Haonan, Zhu Yi, Guo Tiannan, Ji Xiong.  (2022)  Cross-regulome profiling of RNA polymerases highlights the regulatory role of polymerase III on mRNA transcription by maintaining local chromatin architecture.  GENOME BIOLOGY,  23  (1): (1-37).  [PMID:36443871] [10.1186/s13059-022-02812-w]
2. Zhan Yujuan, Chen Qiugu, Song Yue, Wei Xianli, Zhao Tingxiu, Chen Bonan, Li Chengxi, Zhang Wenbo, Jiang Yanjun, Tan Yuhui, Du Biaoyan, Xiao Jianyong, Wang Kun.  (2022)  Berbamine Hydrochloride inhibits lysosomal acidification by activating Nox2 to potentiate chemotherapy-induced apoptosis via the ROS-MAPK pathway in human lung carcinoma cells.  CELL BIOLOGY AND TOXICOLOGY,      [PMID:36070022] [10.1007/s10565-022-09756-8]
3. Zhai Yansheng, Huang Xiaoyan, Zhang Keren, Huang Yuchen, Jiang Yanlong, Cui Jingwei, Zhang Zhe, Chiu Cookson K. C., Zhong Weiye, Li Gang.  (2022)  Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.  Nature Communications,  13  (1): (1-12).  [PMID:35987950] [10.1038/s41467-022-32689-z]
4. Chenchen Ge, Xiong Chen, Dou Wang.  (2024)  An array of femtoliter wells for sensitive detection of copper using click chemistry.  TALANTA,      [PMID:38537359] [10.1016/j.talanta.2024.125973]
5. Yu-Juan Zhan, Chun-Miao Deng, Lin Tang, Shu-Jun Li, Tao-Yang Xu, Xian Wei, Xin-Yi Zhang, Can-Can Zheng, Li Deng, Cui Shao, Zhong-Min Ouyang, Alfred King-Yin Lam, Rong Zhang, Jun Liu, Xing-Yuan Shi, Zhen-Yu Pan, Wei Dai, Ming-Liang He, Simon Law, Xu Li, Xiao-Bing Chen, Cheng Zhou, Bin Li, Wen-Wen Xu.  (2025)  NAT10 Increases Lysosomal Acidification to Promote Esophageal Cancer Metastasis via ac4C Acetylation of ATP6V0E1 mRNA.  Advanced Science,      [PMID:40729677] [10.1002/advs.202502931]
6. Shaoqian Ma, Yantao Hong, Junhan Chen, Jingzhao Xu, Xiaohua Shen.  (2025)  Single-cell nascent transcription reveals sparse genome usage and plasticity.  CELL,      [PMID:41015043] [10.1016/j.cell.2025.09.003]
7. Meichen Li, Yi Peng, Qingqing Xiao, Siyi Chen, Chunjie Zhang, Hongyu Chen, Yue Zhao, Shan Chang, Lu Qiu, Lele Zhang, Xiaoqiang Guo, Qiang Fu.  (2025)  Pharmacological inhibition of PGK1 by genipin reduces inflammation and oxidative damage in osteoarthritis.  PHYTOMEDICINE,      [PMID:41447841] [10.1016/j.phymed.2025.157729]
8. Yuchen Huang, Lexuan Hou, Lin Zhu, Xi Yang, Gang Li.  (2026)  Protocol for covalent ligand discovery via library-versus-proteome screening.  STAR Protocols,  7  (3): (104786).  [PMID:] [10.1016/j.xpro.2026.104786]
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