≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C,Argon charged Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Bis-PEG5-NHS ester is a PEG derivative containing two NHS ester groups. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
Features and Benefits
· Reactive groups: NHS ester (both ends)
· Reactive towards: amino groups (primary amines)
· NHS esters react with—NH2 groups at pH 7-9, forming stable amide bonds
· Water-soluble; compare to non-pegylated BS3 (also soluble) and DSS (water-insoluble)
· Membrane-impermeable, allowing for cell surface labeling
· Irreversibly crosslink proteins or peptides by flexible PEG spacer arms
· Polyethylene glycol spacer arms help maintain conjugate solubility
· Pure compound with defined structure and molecular weight, ensuring reproducible protein-modification effects
· PEG spacer provides unique advantages, including increased stability, reduced tendency toward aggregation and reduced immunogenicity
· Ideal for small molecule or peptide conjugations
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organic acids and derivatives |
| 분류 | Carboxylic acids and derivatives |
| Subclass | Dicarboxylic acids and derivatives |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Dicarboxylic acids and derivatives |
| Alternative Parents | Pyrrolidine-2-ones Dicarboximides Lactams Dialkyl ethers Azacyclic compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds |
| Molecular Framework | Aliphatic heteromonocyclic compounds |
| Substituents | Dicarboxylic acid or derivatives - Pyrrolidone - 2-pyrrolidone - Dicarboximide - Pyrrolidine - Lactam - Organoheterocyclic compound - Ether - Dialkyl ether - Azacycle - Organic oxide - Organic oxygen compound - Carbonyl group - Organooxygen compound - Organonitrogen compound - Organic nitrogen compound - Hydrocarbon derivative - Aliphatic heteromonocyclic compound |
| 설명 | This compound belongs to the class of organic compounds known as dicarboxylic acids and derivatives. These are organic compounds containing exactly two carboxylic acid groups. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | 날짜 | 항목 |
|---|---|---|---|
 B2625163 | Certificate of Analysis | Jun 07, 2025 | B595340 |
| F2517215 | Certificate of Analysis | Jun 07, 2025 | B595340 |
| F2517216 | Certificate of Analysis | Jun 07, 2025 | B595340 |
| F2517217 | Certificate of Analysis | Jun 07, 2025 | B595340 |
| F2517219 | Certificate of Analysis | Jun 07, 2025 | B595340 |
| F2517220 | Certificate of Analysis | Jun 07, 2025 | B595340 |
| F2517221 | Certificate of Analysis | Jun 07, 2025 | B595340 |
| 용해성 | Solubility in DMSO, DCM, DMF |
|---|---|
| 감도 | Heat and moisture sensitive |
| 발화점(°C) | 336 °C |
| 분자량 | 532.500 g/mol |
| XLogP3 | -2.600 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 13 |
| Rotatable Bond Count | 22 |
| Exact Mass | 532.19 Da |
| Monoisotopic Mass | 532.19 Da |
| Topological Polar Surface Area | 174.000 Ų |
| Heavy Atom Count | 37 |
| Formal Charge | 0 |
| Complexity | 707.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
