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BLU945 - Moligand™, ≥98% , Inhibitor of epidermal growth factor receptor, CAS No.2660250-10-0, Inhibitor of epidermal growth factor receptor

CAS: 2660250-10-0 Cat. No.: B608108 분자식: C28H37FN6O3S 분자량: 556.70 PubChem CID: 156538665
COA
BLU945 - Moligand™, ≥98% CAS No(2660250-10-0) by Aladdin Scientific
주문 가능
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
Synonyms
BLU 945 | BLU945 | BLU-945 | AKOS040759965 | UNII-PA4PTH5HL9 | 2660250-10-0 | 3-Isoquinolinamine, N-(2-((3S,4R)-3-fluoro-4-methoxy-1-piperidinyl)-4-pyrimidinyl)-5-(1-methylethyl)-8-((2R,3S)-2-methyl-3-((methylsulfonyl)methyl)-1-azetidinyl)- | GTPL11948 |
Storage
Store at 2-8°C,Protected from light
Shipped In
Wet ice
★
Size
USA
독일 (EU)*
Price
Qty
1mg
B608108-1mg
1 재고 있음
—
US$27.90
5mg
B608108-5mg
1 재고 있음
—
US$79.90
10mg
B608108-10mg
1 재고 있음
—
US$119.90
25mg
B608108-25mg
1 재고 있음
—
US$199.90
50mg
B608108-50mg
1 재고 있음
—
US$339.90
100mg
B608108-100mg
1 재고 있음
—
US$519.90
Enter a quantity for the sizes you want to add.
Bulk / Custom
♡ 위시 리스트 ⇅ 비교하기에 추가 ⎙ Print page
SDS
Safety data
COA
Certificate
DS
Datasheet
SP
Spec sheet
개요 Specifications 이름과 식별자 Documentation Advanced Data 관련 대상(인간) 작용 메커니즘 인증서(CoA, COO, BSE/TSE 및 분석 차트) 화학 및 물리적 특성 솔루션 계산기 리뷰
🧪

Why this grade

Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C,Protected from light Ships Wet ice Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

개요

BLU-945 is a potent, highly selective, reversible epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKIs). BLU-945 can effectively inhibit EGFR with L858R and/or exon 19 deletion mutation, T790M mutation and C797S mutation. BLU-945 can be used for the research of lung cancer including non-small cell lung cancer (NSCLC).

Specifications

동의어
BLU 945 | BLU945 | BLU-945 | AKOS040759965 | UNII-PA4PTH5HL9 | 2660250-10-0 | 3-Isoquinolinamine, N-(2-((3S,4R)-3-fluoro-4-methoxy-1-piperidinyl)-4-pyrimidinyl)-5-(1-methylethyl)-8-((2R,3S)-2-methyl-3-((methylsulfonyl)methyl)-1-azetidinyl)- | GTPL11948 |
사양 및 순도
Moligand™, ≥98%
보관 조건
Store at 2-8°C,Protected from light
배송
Wet ice
이 제품은 콜드 체인 배송이 필요합니다.지상 및 기타 경제 서비스는 사용할 수 없습니다.
등급
Moligand™
작업 유형
INHIBITOR
작동 메커니즘
Inhibitor of epidermal growth factor receptor
순수함
≥98%
이름과 식별자
Pubchem Sid528763453
이성체 SMILES C[C@@H]1[C@H](CN1C2=C3C=NC(=CC3=C(C=C2)C(C)C)NC4=NC(=NC=C4)N5CC[C@H]([C@H](C5)F)OC)CS(=O)(=O)C
PubChem CID 156538665
분자량 556.70

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

관련 대상(인간)
EGFR Tclin Epidermal growth factor receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
EGFR Tclin Epidermal growth factor receptor erbB1 (33727 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NCI-H1975 (4994 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
작용 메커니즘
인증서(CoA, COO, BSE/TSE 및 분석 차트)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

12 results found

Lot NumberCertificate Type날짜항목
J2410264Certificate of AnalysisJul 08, 2024 B608108
J2410265Certificate of AnalysisJul 08, 2024 B608108
J2410266Certificate of AnalysisJul 08, 2024 B608108
J2410267Certificate of AnalysisJul 08, 2024 B608108
J2410268Certificate of AnalysisJul 08, 2024 B608108
J2410272Certificate of AnalysisJul 08, 2024 B608108
J2410273Certificate of AnalysisJul 08, 2024 B608108
J2410274Certificate of AnalysisJul 08, 2024 B608108
J2410275Certificate of AnalysisJul 08, 2024 B608108
J2410276Certificate of AnalysisJul 08, 2024 B608108
J2410306Certificate of AnalysisJul 08, 2024 B608108
J2410307Certificate of AnalysisJul 08, 2024 B608108

Show more ⌵

화학 및 물리적 특성
감도Light sensitive
분자량556.700 g/mol
XLogP34.600
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count10
Rotatable Bond Count8
Exact Mass556.263 Da
Monoisotopic Mass556.263 Da
Topological Polar Surface Area109.000 Ų
Heavy Atom Count39
Formal Charge0
Complexity921.000
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
솔루션 계산기
리뷰

고객 리뷰

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Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

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View related series

epidermal growth factor receptor Inhibitor (73) Receptor Tyrosine Kinase (2793)
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