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(-)-BO 2367, an antimicrobial quinolone , is a strong mammalian and bacterial topoisomerase II inhibitor. (-)-BO 2367 shows IC 50 values with 3.8 μM, 0.5 μM, and 1 μM against the DNA relaxation activity of L1210 topoisomerase II and the supercoiling activities of Escherichia coli gyrase and Micrococcus luteus gyrase, respectively. (-)-BO 2367 is a potent antitumor agent.
| CAS | 145902-81-4 |
|---|---|
| 보관 조건 | Store at -20°C |
| 배송 | Ice chest + Ice pads |
| Product Description | (-)-BO 2367, an antimicrobial quinolone , is a strong mammalian and bacterial topoisomerase II inhibitor. (-)-BO 2367 shows IC 50 values with 3.8 μM, 0.5 μM, and 1 μM against the DNA relaxation activity of L1210 topoisomerase II and the supercoiling activities of Escherichia coli gyrase and Micrococcus luteus gyrase, respectively. (-)-BO 2367 is a potent antitumor agent. |