BPD , CAS No.213481-12-0

CAS: 213481-12-0 Cat. No.: B1432977 분자식: C₁₇H₁₀O₅ 분자량: 294.26 EC 번호: 803-332-1 PubChem CID: 10286243

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

개요

BPD is a COX-2 and TAK1-NF-κB inhibitor, with an IC 50 of 18.5 μM for COX-2. BPD inhibits the expression of iNOS , TNF-α, IL-6 and IL-1β at the transcriptional level. BPD has anti-inflammatory activity. BPD can inhibit Carrageenan-induced paw oedema and LPS-induced septic death.

Specifications

보관 조건

Store at -20°C

배송

Ice chest + Ice pads

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작업 유형

INHIBITOR

이름과 식별자

• 정식 스마일: C1OC2=C(O1)C=C(C=C2)C3=C(C(=O)OC3=O)C4=CC=CC=C4
• IUPAC Name: 3-(1,3-benzodioxol-5-yl)-4-phenylfuran-2,5-dione
• InChIKey: IMHGOAWBSJVILI-UHFFFAOYSA-N
• INCHI: 1S/C17H10O5/c18-16-14(10-4-2-1-3-5-10)15(17(19)22-16)11-6-7-12-13(8-11)21-9-20-12/h1-8H,9H2
• 이성체 SMILES: C1OC2=C(O1)C=C(C=C2)C3=C(C(=O)OC3=O)C4=CC=CC=C4
• WGK 독일: 3
• PubChem CID: 10286243
• 분자량: 294.26

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Phenylpropanoids and polyketides
    • 분류 Stilbenes

• Kingdom: Organic compounds
• Superclass: Phenylpropanoids and polyketides
• 분류: Stilbenes
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Stilbenes
• Alternative Parents: Benzodioxoles Dicarboxylic acids and derivatives Butenolides Benzene and substituted derivatives Carboxylic acid anhydrides Oxacyclic compounds Acetals Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Stilbene - Benzodioxole - Monocyclic benzene moiety - 2-furanone - Dicarboxylic acid or derivatives - Benzenoid - Carboxylic acid anhydride - Dihydrofuran - Oxacycle - Carboxylic acid derivative - Acetal - Organoheterocyclic compound - Carbonyl group - Hydrocarbon derivative - Organic oxide - Organic oxygen compound - Organooxygen compound - Aromatic heteropolycyclic compound
• 설명: This compound belongs to the class of organic compounds known as stilbenes. These are organic compounds containing a 1,2-diphenylethylene moiety. Stilbenes (C6-C2-C6 ) are derived from the common phenylpropene (C6-C3) skeleton building block. The introduction of one or more hydroxyl groups to a phenyl ring lead to stilbenoids.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y