bpV(HOpic) - ≥95% , CAS No.722494-26-0

CAS: 722494-26-0 Cat. No.: B334661 분자식: C₆H₄K₂NO₈V 분자량: 347.24 EC 번호: 806-224-2 PubChem CID: 54692867

등급 & 순도 ≥95%

Synonyms

Dipotassium bisperoxo (5-hydroxypyridine-2-carboxyl) oxovanadate (V) | Bisperoxovanadium(HOpic) | (5-hydroxy-2-pyridinecarboxylato-κN1,κO2)oxodiperoxy-vanadate(2-), dipotassium

Storage

Protected from light,Store at -20°C

Shipped In

Ice chest + Ice pads

개요

bpV(HOpic) is a bisperoxo oxovanadate dipotassium salt coordinated to 5-hydroxypyridine-2-carboxylate. This vanadium compound has been shown to be a potent inhibitor of protein phosphotyrosine phosphatase (PTP) and PTEN, and has been described to act as an insulin mimetic. This compound has been shown to activate the insulin receptor kinase of hepatoma cells, stimulate lipogenesis in adipocytes, and to enhance PI3K/Akt signaling that could prevent ischemia-reperfusion (I/R) injury to the myocardium.

사양

동의어

Dipotassium bisperoxo (5-hydroxypyridine-2-carboxyl) oxovanadate (V) | Bisperoxovanadium(HOpic) | (5-hydroxy-2-pyridinecarboxylato-κN1,κO2)oxodiperoxy-vanadate(2-), dipotassium

사양 및 순도

≥95%

생화학 및 생리적 메커니즘

bpV(OHpic) is a bisperoxovanadium inhibitor of protein phosphotyrosine phosphatases with selectivity for PTEN, phosphatase and tensin homolog, a tumour suppressor phosphatase involved in cell cycle regulation. IC50 values for bpV(HOpic) are 14 nM for PTEN

보관 조건

Protected from light,Store at -20°C

배송

Ice chest + Ice pads

이 제품은 콜드 체인 배송이 필요합니다.지상 및 기타 경제 서비스는 사용할 수 없습니다.

순수함

≥95%

이름과 식별자

이성체 SMILES

C1=CC(=NC=C1[O-])C(=O)O.OO.OO.O=[V].[K+].[K+]

WGK 독일

3

PubChem CID

54692867

분자량

347.24

화학 및 물리적 특성

• 용해성: Soluble in cold water (easily), and DMSO. Note: This product is not stable in water. Starts decomposition immediately after solubilization. Rate of decomposition is slower in dry DMSO.
• 감도: Light & Moisture sensitive

자주 묻는 질문

What is the purity of this product?

This product is supplied at ≥95% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C, protected from light. The material is light-sensitive — keep it in its original opaque or amber container.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 722494-26-0, the molecular formula is C6H4K2NO8V, and the molecular weight is 347.24 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.