Br-PEG4-OH - Moligand™, ≥97% , CAS No.85141-94-2

CAS: 85141-94-2 Cat. No.: B412703 Molecular Weight: 257.12 EC Number: 886-530-0

GRADE & PURITY Moligand™, ≥97%

Synonyms

SCHEMBL10961934 | F12154 | Ethanol, 2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]- | 2-[2-[2-(2-Bromoethoxy)ethoxy]ethoxy]ethanol | 2-(2-(2-(2-bromoethoxy)ethoxy)ethoxy)ethan-1-ol | Bromo-PEG4-alcohol | 2-[2-[2-(2-Bromoethoxy)ethoxy]ethoxy]-ethanol | HY-130512 |

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Application

Antibody Drug Conjugates(ADC), Drug Delivery, Surface Modification, PEGylation of Protein, Peptide & Oligo

Specifications

Synonyms

SCHEMBL10961934 | F12154 | Ethanol, 2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]- | 2-[2-[2-(2-Bromoethoxy)ethoxy]ethoxy]ethanol | 2-(2-(2-(2-bromoethoxy)ethoxy)ethoxy)ethan-1-ol | Bromo-PEG4-alcohol | 2-[2-[2-(2-Bromoethoxy)ethoxy]ethoxy]-ethanol | HY-130512 |

Specifications & Purity

Moligand™, ≥97%

Biochemical and Physiological Mechanisms

Br-PEG4-OH is a PEG-based PROTAC linker that is applicable to the synthesis of PROTACs.

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Purity

≥97%

Names and Identifiers

• Canonical Smiles: C(COCCOCCOCCBr)O
• IUPAC Name: 2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]ethanol
• InChIKey: CERQCRALBKUCTF-UHFFFAOYSA-N
• INCHI: 1S/C8H17BrO4/c9-1-3-11-5-7-13-8-6-12-4-2-10/h10H,1-8H2
• Isomeric SMILES: C(COCCOCCOCCBr)O
• Molecular Weight: 257.12
• Reaxy-Rn: 4739091
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=4739091&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic oxygen compounds
    • Class Organooxygen compounds
      • Subclass Ethers
        • Level5 Dialkyl ethers
          • Level6 Polyethylene glycols

• Kingdom: Organic compounds
• Superclass: Organic oxygen compounds
• Class: Organooxygen compounds
• Subclass: Ethers
• Intermediate Tree Nodes: Dialkyl ethers
• Direct Parent: Polyethylene glycols
• Alternative Parents: Primary alcohols Organobromides Hydrocarbon derivatives Alkyl bromides
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Polyethylene glycol - Hydrocarbon derivative - Primary alcohol - Organobromide - Organohalogen compound - Alkyl halide - Alkyl bromide - Alcohol - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as polyethylene glycols. These are oligomers or polymers of ethylene oxide, with the general formula (C2H4O)n (with n>=3).
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Solubility (25°C) In vitro
• Molecular Weight: 257.120 g/mol
• XLogP3: -0.100
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 10
• Exact Mass: 256.031 Da
• Monoisotopic Mass: 256.031 Da
• Topological Polar Surface Area: 47.900 Ų
• Heavy Atom Count: 13
• Formal Charge: 0
• Complexity: 92.200
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

1. Jiongcheng Lu, Jiawei Lin, Ran Chen, Qian Sun, Zhenxing Wang, Wen Huang, Lili Cai, Xuetao Shi, Meng Zhang, Kaojin Wang, Lin Wang, Yong-Guang Jia, Xiaoxia Zhu.  (2025)  3D Printing of α-Amylase-Illuminated Fluorescent Devices for Dynamic Information Storage and Encryption.  Aggregate,      [PMID:] [10.1002/agt2.70153]

2. Wenjing Li, Ming Lei, Zongwen Tan, Leilei Zhang, Xueyang Fang, Tao Zhang.  (2025)  Programmatically Controllable Activation of Sonodynamic Therapeutics with Bioorthogonal-Based Mitochondria-Specific Exogenous Agents toward Accurate Tumor Elimination.  ACS Applied Materials & Interfaces,      [PMID:40525768] [10.1021/acsami.5c04425]