Carnosol - 10mM in DMSO , CAS No.5957-80-2

Name: Carnosol - 10mM in DMSO , CAS No.5957-80-2
SKU: C424963
Availability: InStock

CAS: 5957-80-2 Cat. No.: C424963 분자식: C₂₀H₂₆O₄ 분자량: 330.42 EC 번호: 995-852-1

2 Citations COA

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Carnosol - 10mM in DMSO CAS No(5957-80-2) by Aladdin Scientific

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주문 가능

GRADE & PURITY 10mM in DMSO

Synonyms

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

개요 Specifications 이름과 식별자 Documentation Advanced Data Taxonomic Classification 3D 구조 관련 대상(인간) 관련 대상(비인간) 작용 메커니즘 인증서(CoA, COO, BSE/TSE 및 분석 차트) 화학 및 물리적 특성 자주 묻는 질문과 기사 Citations of This Product 참고 문헌 솔루션 계산기 리뷰

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Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 2 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

개요

Carnosol is a naturally occurring phenolic diterpene found in rosemary. It has anti-oxidant, anti-inflammatory and anti-cancer activities.
Is a polyphenolic antioxidants, a major component of plant Diego Rosemary. Prevention and quality potential role in Alzheimer's disease, Parkinson's disease and other neurological diseases.

Specifications

동의어

사양 및 순도

10mM in DMSO

생화학 및 생리적 메커니즘

A phenolic diterpene with antioxidant and anticarcinogenic activities. .Anti-oxidant and anticancer agent (IC 50 values are 9 and 82 μM for LPS-stimulated NO production and MCF-7 cellsrespectively). Inhibits NFκB and COX-2 induction. Targets PI3K/Akt and

보관 조건

Store at -80°C

배송

Dry ice packs + Cold packs

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작업 유형

INHIBITOR

이름과 식별자

Pubchem Sid	528763879
정식 스마일	CC(C)C1=C(C(=C2C(=C1)C3CC4C2(CCCC4(C)C)C(=O)O3)O)O
IUPAC Name	(1R,8S,10S)-3,4-dihydroxy-11,11-dimethyl-5-propan-2-yl-16-oxatetracyclo[6.6.2.01,10.02,7]hexadeca-2,4,6-trien-15-one
InChIKey	XUSYGBPHQBWGAD-PJSUUKDQSA-N
INCHI	1S/C20H26O4/c1-10(2)11-8-12-13-9-14-19(3,4)6-5-7-20(14,18(23)24-13)15(12)17(22)16(11)21/h8,10,13-14,21-22H,5-7,9H2,1-4H3/t13-,14-,20+/m0/s1
이성체 SMILES	CC(C)C1=C(C(=C2C(=C1)[C@@H]3C[C@@H]4[C@@]2(CCCC4(C)C)C(=O)O3)O)O
WGK 독일	3
분자량	330.42
Reaxy-Rn	1296666
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1296666&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Lipids and lipid-like molecules
  - 분류 Prenol lipids
    - Subclass Terpene lactones

Kingdom	Organic compounds
Superclass	Lipids and lipid-like molecules
분류	Prenol lipids
Subclass	Terpene lactones
Intermediate Tree Nodes	Not available
Direct Parent	Diterpene lactones
Alternative Parents	Diterpenoids Phenanthrenes and derivatives Tetralins 2-benzopyrans Delta valerolactones 1-hydroxy-4-unsubstituted benzenoids Oxanes Carboxylic acid esters Oxacyclic compounds Monocarboxylic acids and derivatives Organic oxides Hydrocarbon derivatives Carbonyl compounds
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	Diterpene lactone - Diterpenoid - Phenanthrene - Benzopyran - Isochromane - 2-benzopyran - Tetralin - 1-hydroxy-4-unsubstituted benzenoid - Delta valerolactone - Delta_valerolactone - Benzenoid - Oxane - Carboxylic acid ester - Lactone - Carboxylic acid derivative - Oxacycle - Organoheterocyclic compound - Monocarboxylic acid or derivatives - Hydrocarbon derivative - Organic oxygen compound - Organic oxide - Organooxygen compound - Carbonyl group - Aromatic heteropolycyclic compound
설명	This compound belongs to the class of organic compounds known as diterpene lactones. These are diterpenoids containing a lactone moiety.
External Descriptors	Abietanes
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

3D 구조

관련 대상(비인간)

PTGES Prostaglandin E synthase (10 Activities)

Discover Target: PTGES

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Pseudomonas aeruginosa (123386 Activities)

분자량	330.400 g/mol
XLogP3	4.400
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	1
Exact Mass	330.183 Da
Monoisotopic Mass	330.183 Da
Topological Polar Surface Area	66.800 Å²
Heavy Atom Count	24
Formal Charge	0
Complexity	542.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	3
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

1. Xie Lixia, Li Zhineng, Li Haitao, Sun Jiayu, Liu Xueying, Tang Jianxin, Lin Xizhu, Xu Laijun, Zhu Yuefang, Liu Zhi, Wang Tong. (2022) Fast Quantitative Determination of Principal Phenolic Anti-oxidants in Rosemary Using Ultrasound-Assisted Extraction and Chemometrics-Enhanced HPLC–DAD Method. Food Analytical Methods, 16 (2): (386-400). [PMID:] [10.1007/s12161-022-02421-0]
2. Xin-Yu Liu, Wen-Zhu Wang, Song-Po Yao, Xue-Ying Li, Rui-Min Han, Dangquan Zhang, Zhijun Zhao, Yapei Wang, Jian-Ping Zhang. (2024) Antioxidation Activity Enhancement by Intramolecular Hydrogen Bond and Non-Browning Mechanism of Active Ingredients in Rosemary: Carnosic Acid and Carnosol. JOURNAL OF PHYSICAL CHEMISTRY B, [PMID:39073136] [10.1021/acs.jpcb.4c02949]

Carnosol - 10mM in DMSO , CAS No.5957-80-2

Why this grade

Storage & shipping

Quality documents

Literature proof

개요

Specifications

Documentation

📋 Safety Data Sheet (SDS)

✅ Certificate of Analysis (COA)

📊 Datasheet

🔬 Specification Sheet

Advanced Data

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

고객 리뷰

📚 Citations by Application

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