(-)-카리오필렌 산화물 - ≥99%(GC), 거울상 이성질체의 합계 , CAS No.1139-30-6

CAS: 1139-30-6 Cat. No.: C345753 분자식: C₁₅H₂₄O 분자량: 220.35 EC 번호: 214-519-7

GRADE & PURITY ≥99%(GC), sum of enantiomers

Synonyms

(-)Carophyllene oxide | [1R-(1R*,4R*,6R*,10S*)]- (-)-Epoxydihydrocaryophyllene (-)-<>-Caryophyllene epoxide (-)-<>-Caryophyllene oxide 4,11,11-Trimethyl-8-methylene-5-oxatricyclo(8.2.0.0(4,6))dodecane | C16908 | (-)-Caryophyllene oxide, >=99.0

Storage

2-8°C, 빛으로부터 보호, 건조 보관

Shipped In

젖은 얼음

개요

(-)-카리오필렌 옥사이드 또는 β-카리오필렌 옥사이드(BCPO)는 천연 식물 화합물, 바이사이클릭 세스키테르펜 및 β-카리오필렌(BCP)의 산화 유도체입니다. 강한 나무 냄새가 납니다. BCPO는 바질, 샐비어, 어성초와 같은 많은 식품 및 향신료 식물과 에센셜 오일에서 흔히 발견됩니다. 화장품 및 식품 첨가물로 널리 사용됩니다.

응용 분야

(-)-카리오필렌 옥사이드가 사용되었습니다:

그람 양성, 그람 음성 및 효모 균주에 대한 효과를 연구하기 위한 항균제로서

화염 이온화 검출 가스 크로마토그래피(GC-FID)를 사용하여 마르칸티아 폴리모파 추출물의 구성 성분을 정량 분석하는 상용 표준으로서

가스 크로마토그래피-질량 분석법(GC-MS)을 사용하여 아킬레아 리구스티카 에센셜 오일 성분의 이성질체 비율을 분석하는 참조 표준으로 사용됩니다

Specifications

동의어

(-)Carophyllene oxide | [1R-(1R*,4R*,6R*,10S*)]- (-)-Epoxydihydrocaryophyllene (-)-<>-Caryophyllene epoxide (-)-<>-Caryophyllene oxide 4,11,11-Trimethyl-8-methylene-5-oxatricyclo(8.2.0.0(4,6))dodecane | C16908 | (-)-Caryophyllene oxide, >=99.0

사양 및 순도

≥99%(GC), 거울상 이성질체의 합계

생화학 및 생리적 메커니즘

β-카리오필렌 옥사이드는 항산화, 항염증 및 항바이러스 작용을 하는 강력한 항암제로, 쥐와 인간의 간 미소체에서 약물 대사 효소인 사이토크롬 P4503A(CYP3A)의 활성을 강력하게 억제하는 물질입니다

보관 조건

2-8°C, 빛으로부터 보호, 건조 보관

배송

젖은 얼음

순수함

≥99%(GC)

이름과 식별자

• Pubchem Sid: 488191998
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488191998
• 정식 스마일: CC1(CC2C1CCC3(C(O3)CCC2=C)C)C
• IUPAC Name: (1R,4R,6R,10S)-4,12,12-trimethyl-9-methylidene-5-oxatricyclo[8.2.0.04,6]dodecane
• InChIKey: NVEQFIOZRFFVFW-RGCMKSIDSA-N
• INCHI: 1S/C15H24O/c1-10-5-6-13-15(4,16-13)8-7-12-11(10)9-14(12,2)3/h11-13H,1,5-9H2,2-4H3/t11-,12-,13-,15-/m1/s1
• 이성체 SMILES: C[C@@]12CC[C@@H]3[C@H](CC3(C)C)C(=C)CC[C@H]1O2
• WGK 독일: 2
• RTECS: RP5530000
• 분자량: 220.35
• Reaxy-Rn: 148213
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=148213&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Lipids and lipid-like molecules
    • 분류 Prenol lipids
      • Subclass Sesquiterpenoids

• Kingdom: Organic compounds
• Superclass: Lipids and lipid-like molecules
• 분류: Prenol lipids
• Subclass: Sesquiterpenoids
• Intermediate Tree Nodes: Not available
• Direct Parent: Sesquiterpenoids
• Alternative Parents: Oxacyclic compounds Epoxides Dialkyl ethers Hydrocarbon derivatives
• Molecular Framework: Aliphatic heteropolycyclic compounds
• Substituents: Caryophyllane sesquiterpenoid - Sesquiterpenoid - Oxacycle - Organoheterocyclic compound - Ether - Oxirane - Dialkyl ether - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Aliphatic heteropolycyclic compound
• 설명: This compound belongs to the class of organic compounds known as sesquiterpenoids. These are terpenes with three consecutive isoprene units.
• External Descriptors: Caryophyllane sesquiterpenoids

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

관련 대상(인간)

TRPV1 Tclin Vanilloid receptor (8273 Activities)

Discover Target: TRPV1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HL (112 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

관련 대상(비인간)

Chlamydia pneumoniae (241 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Tetranychus urticae (2600 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PC-12 (7051 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Ileum (29 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Jejunum (38 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

작용 메커니즘

화학 및 물리적 특성

• 감도: Light sensitive
• 녹는점(°C): 62-63° C (lit.)
• 분자량: 220.350 g/mol
• XLogP3: 3.600
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 220.183 Da
• Monoisotopic Mass: 220.183 Da
• Topological Polar Surface Area: 12.500 Ų
• Heavy Atom Count: 16
• Formal Charge: 0
• Complexity: 330.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 4
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

참고 문헌

1. Pengfei Yang, Lingqi Kong, Qiongbo Wang, Qiang Liu, Xiujin Duan, Chen Hu, Zhengbo Feng, Qi Yang, Huabo Jv.  (2026)  Analysis of volatile compounds in Aglaia odorata flower extracts with different possessing methods by HS-SPME-GC-MS and E-nose.  Frontiers in Chemistry,      [PMID:41867951] [10.3389/fchem.2026.1746408]