CCR8 antagonist 2 - ≥99% , CAS No.2756350-98-6

CAS: 2756350-98-6 Cat. No.: C650241 분자식: C₂₃H₃₀ClN₃O₃S 분자량: 464.02

등급 & 순도 ≥99%

Storage

Store at 2-8°C,Protected from light,Desiccated

Shipped In

Wet ice

개요

CCR8 antagonist 2 is a potent antagonist of CCR8 . CCR8 (C-C Motif Chemokine Receptor 8) is predominantly expressed on Treg cells and Th2 cells, but not on Th1 cells. CCR8 antagonist 2 inhibits CCR8 activity, which may be used in the research of diseases mediated by CCR8 , such as cancer , and/or neuropathic pain (extracted from patent WO2022000443A1, compound 220)

Form:Solid

IC50& Target:CCR8

사양

사양 및 순도

≥99%

생화학 및 생리적 메커니즘

CCR8 antagonist 2 is a potent antagonist of CCR8 . CCR8 (C-C Motif Chemokine Receptor 8) is predominantly expressed on Treg cells and Th2 cells, but not on Th1 cells. CCR8 antagonist 2 inhibits CCR8 activity, which may be used in the research of diseases

보관 조건

Store at 2-8°C,Protected from light,Desiccated

배송

Wet ice

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작업 유형

ANTAGONIST

순수함

≥99%

이름과 식별자

분자량

464.02

화학 및 물리적 특성

• 용해성: DMSO : 4 mg/mL (8.62 mM; ultrasonic and warming and heat to 60°C)