CEP-14083 , CAS No.856692-39-2
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SKU
C1450354
CEP-14083 is a ATP-competitive ALK kinase inhibitor with an IC 50 value in enzymatic assays of 2 nM. CEP-14083 also inhibits other kinases, such as insulin receptor ( IR ), vascular endothelial growth factor receptor 2 ( VEGFR2 ), angiopoietin-1 receptor ( TIE2 ) and dual leucine zipper kinase ( DLK ). CEP-14083 suppresses CD274 mRNA expression and the NPM/ALK function in the NPM/ALK-carrying T cell lymphoma (ALK+TCL) cells. CEP-14083 is promising for research of lymphoma.
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| CAS | 856692-39-2 |
|---|---|
| 보관 조건 | Store at -20°C |
| 배송 | Ice chest + Ice pads |
| Product Description | CEP-14083 is a ATP-competitive ALK kinase inhibitor with an IC 50 value in enzymatic assays of 2 nM. CEP-14083 also inhibits other kinases, such as insulin receptor ( IR ), vascular endothelial growth factor receptor 2 ( VEGFR2 ), angiopoietin-1 receptor ( TIE2 ) and dual leucine zipper kinase ( DLK ). CEP-14083 suppresses CD274 mRNA expression and the NPM/ALK function in the NPM/ALK-carrying T cell lymphoma (ALK+TCL) cells. CEP-14083 is promising for research of lymphoma. |
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