Explore small molecules mapped to protein tyrosine kinase and receptor tyrosine kinase signaling for growth-factor biology and oncology research. This category supports focused screening and pathway studies around phosphorylation-driven signaling networks.
Protein Tyrosine Kinase/RTK
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- GW 583340 dihydrochlorideMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%(HPLC)Out of Stock Item #: G286712View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[2-[(2-methylsulfonylethylamino)methyl]-1,3-thiazol-4-yl]quinazolin-4-amine;dihydrochloride
- SMILES
- CS(=O)(=O)CCNCC1=NC(=CS1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl.Cl.Cl
- InChIKey
- WIMITXDBYLKRKB-UHFFFAOYSA-N
- InChI
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- Synonyms
- N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[2-[[[2-(methylsulfonyl)ethyl]amino]methyl]-4-thiazolyl]-4-quinazoli...
- GSK1904529ACAS: 1089283-49-7 Formula: C44H47F2N9O5S Molecular Weight: 851.96Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%In Stock Item #: G127237View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
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- SMILES
- CCC1=CC(=C(C=C1N2CCC(CC2)N3CCN(CC3)S(=O)(=O)C)OC)NC4=NC=CC(=N4)C5=C(N=C6N5C=CC=C6)C7=CC(=C(C=C7)OC)C(=O)NC8=C(C=CC=C8F)F
- InChIKey
- MOSKATHMXWSZTQ-UHFFFAOYSA-N
- InChI
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- Synonyms
- MOSKATHMXWSZTQ-UHFFFAOYSA-N | SB18897 | Trifluralin [ANSI:BSI:ISO] | AMY24202 | A24618 | GSK 4529 | IGF-1R inhibitor ...
- NBI 31772CAS: 374620-70-9 Formula: C17H11NO7 Molecular Weight: 341.27In Stock Item #: N287388View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1-(3,4-dihydroxybenzoyl)-6,7-dihydroxyisoquinoline-3-carboxylic acid
- SMILES
- C1=CC(=C(C=C1C(=O)C2=NC(=CC3=CC(=C(C=C32)O)O)C(=O)O)O)O
- InChIKey
- ZCMFEWUYBFMLIN-UHFFFAOYSA-N
- InChI
- 1S/C17H11NO7/c19-11-2-1-7(4-12(11)20)16(23)15-9-6-14(22)13(21)5-8(9)3-10(18-15)17(24)25/h1-6,19-22H,(H,24,25)
- Synonyms
- BDBM50106431 | DTXSID80741040 | UNII-7DYH3XNP6H | 1-[(3,4-Dioxocyclohexa-1,5-dien-1-yl)(hydroxy)methylidene]-6,7-dihy...
- AEE788 (NVP-AEE788), Vascular endothelial growth factor receptor 1 inhibitorCAS: 497839-62-0 Formula: C27H32N6 Molecular Weight: 440.58In Stock Item #: A126830View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 6-[4-[(4-ethylpiperazin-1-yl)methyl]phenyl]-N-[(1R)-1-phenylethyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
- SMILES
- CCN1CCN(CC1)CC2=CC=C(C=C2)C3=CC4=C(N3)N=CN=C4NC(C)C5=CC=CC=C5
- InChIKey
- OONFNUWBHFSNBT-HXUWFJFHSA-N
- InChI
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- Synonyms
- 6-[4-[(4-ethylpiperazin-1-yl)methyl]phenyl]-N-[(1R)-1-phenylethyl]-7H-pyrrolo[3,2-e]pyrimidin-4-amine | 7,9-Dimethyl-...
- GNF-2Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%In Stock Item #: G126166View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 3-[6-[4-(trifluoromethoxy)anilino]pyrimidin-4-yl]benzamide
- SMILES
- C1=CC(=CC(=C1)C(=O)N)C2=CC(=NC=N2)NC3=CC=C(C=C3)OC(F)(F)F
- InChIKey
- WEVYNIUIFUYDGI-UHFFFAOYSA-N
- InChI
- 1S/C18H13F3N4O2/c19-18(20,21)27-14-6-4-13(5-7-14)25-16-9-15(23-10-24-16)11-2-1-3-12(8-11)17(22)26/h1-10H,(H2,22,26)(H,23,24,25)
- Synonyms
- HMS3265C23 | Bcr-abl inhibitor GNF-2 | HMS3333I20 | SB19395 | SW219739-1 | 3-[6-(4-trifluoromethoxyphenyl-amino)-pyri...
- NVP-ADW742CAS: 475488-23-4 Formula: C28H31N5O Molecular Weight: 453.58In Stock Item #: N126810View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 5-(3-phenylmethoxyphenyl)-7-[3-(pyrrolidin-1-ylmethyl)cyclobutyl]pyrrolo[2,3-d]pyrimidin-4-amine
- SMILES
- C1CCN(C1)CC2CC(C2)N3C=C(C4=C(N=CN=C43)N)C5=CC(=CC=C5)OCC6=CC=CC=C6
- InChIKey
- LSFLAQVDISHMNB-UHFFFAOYSA-N
- InChI
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- Synonyms
- 5-(3-Benzyloxyphenyl)-7-[trans-3-[(pyrrolidin-1-yl)methyl]cyclobutyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine | AS-56233 |...
- GW441756CAS: 504433-23-2 Formula: C17H13N3O Molecular Weight: 275.3In Stock Item #: G129825View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (3Z)-3-[(1-methylindol-3-yl)methylidene]-1H-pyrrolo[3,2-b]pyridin-2-one
- SMILES
- CN1C=C(C2=CC=CC=C21)C=C3C4=C(C=CC=N4)NC3=O
- InChIKey
- NXNQLECPAXXYTR-LCYFTJDESA-N
- InChI
- 1S/C17H13N3O/c1-20-10-11(12-5-2-3-7-15(12)20)9-13-16-14(19-17(13)21)6-4-8-18-16/h2-10H,1H3,(H,19,21)/b13-9-
- Synonyms
- GW441756 hydrochloride | 3-(1-Methyl-1H-indol-3-ylmethylene)-1,3-dihydro-pyrrolo[3,2-b]pyridin-2-one | BRD-K04146668-...
- ZM306416 hydrochlorideIn Stock Item #: Z276165View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-(4-chloro-2-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine;hydrochloride
- SMILES
- COC1=C(C=C2C(=C1)C(=NC=N2)NC3=C(C=C(C=C3)Cl)F)OC.Cl
- InChIKey
- SCUXIROMWPQVJO-UHFFFAOYSA-N
- InChI
- 1S/C16H13ClFN3O2.ClH/c1-22-14-6-10-13(7-15(14)23-2)19-8-20-16(10)21-12-4-3-9(17)5-11(12)18;/h3-8H,1-2H3,(H,19,20,21);1H
- Synonyms
- 4-[(4'-Chloro-2'-fluoro)phenylamino]-6,7-dimethoxyquinazolinehydrochloride
- Foretinib (GSK1363089), Vascular endothelial growth factor receptor inhibitorMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%In Stock Item #: F127011View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1-N'-[3-fluoro-4-[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxyphenyl]-1-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
- SMILES
- COC1=CC2=C(C=CN=C2C=C1OCCCN3CCOCC3)OC4=C(C=C(C=C4)NC(=O)C5(CC5)C(=O)NC6=CC=C(C=C6)F)F
- InChIKey
- CXQHYVUVSFXTMY-UHFFFAOYSA-N
- InChI
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- Synonyms
- 81FH7VK1C4 | Foretinib [USAN:INN] | N-(3-FLUORO-4-((6-METHOXY-7-(3-(MORPHOLIN-4-YL)PROPOXY)QUINOLIN-4-YL)OXY) PHENYL)...
- Lestaurtinib, Tyrosine-protein kinase receptor RET inhibitorCAS: 111358-88-4 Formula: C26H21N3O4 Molecular Weight: 439.46Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%In Stock Item #: L275009View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
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- SMILES
- CC12C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)(CO)O
- InChIKey
- UIARLYUEJFELEN-LROUJFHJSA-N
- InChI
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- Synonyms
- SPM-924 | (5S,6S,8R)-6-hydroxy-6-(hydroxymethyl)-5-methyl-7,8,14,15-tetrahydro-5H-16-oxa-4b,8a,14-triaza-5,8-methanod...
- ZM 449829Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%Out of Stock Item #: Z275707View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1-naphthalen-2-ylprop-2-en-1-one
- SMILES
- C=CC(=O)C1=CC2=CC=CC=C2C=C1
- InChIKey
- FOTCGZPFSUWZBN-UHFFFAOYSA-N
- InChI
- 1S/C13H10O/c1-2-13(14)12-8-7-10-5-3-4-6-11(10)9-12/h2-9H,1H2
- Synonyms
- 1-(2-Naphthalenyl)-2-propen-1-one
- ZM 39923 HClCAS: 1021868-92-7 Formula: C23H25NO.HCl Molecular Weight: 367.91Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%In Stock Item #: Z129618View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 3-[benzyl(propan-2-yl)amino]-1-naphthalen-2-ylpropan-1-one;hydrochloride
- SMILES
- CC(C)N(CCC(=O)C1=CC2=CC=CC=C2C=C1)CC3=CC=CC=C3.Cl
- InChIKey
- NJTUORMLOPXPBY-UHFFFAOYSA-N
- InChI
- 1S/C23H25NO.ClH/c1-18(2)24(17-19-8-4-3-5-9-19)15-14-23(25)22-13-12-20-10-6-7-11-21(20)16-22;/h3-13,16,18H,14-15,17H2,1-2H3;1H
- Synonyms
- DTXSID301017077 | 3-BENZYLISOPROPYLAMINO-1-NAPHTHALEN-2-YL-PROPAN-1-ONE HYDROCHLORIDE | ZM39923 HCl;ZM-39923 HCl | 3-...
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