Ceramide trihexosides - ≥98% , CAS No.71965-57-6

CAS: 71965-57-6 Cat. No.: C329702 분자식: C₆₀H₁₁₃NO₁₈(tetracosanoyl) 분자량: 1136.6(tetracosanoyl)

GRADE & PURITY ≥98%

Synonyms

Globotriaosylceramide | CTH | Gb3 | 1-O-(O-α-D-galactopyranosyl-(1→4)-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranosyl)-ceramide

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

개요

Globotriaosycleramides are glycosphingolipids found in mammalian cell membranes that are synthesized from lactosylceramides. They act as receptors for Shiga and Shiga-like toxins in vitro and in vivo. Globotriaosylceramides accumulate in endothelial cells, pericytes, vascular smooth muscle cells, renal epithelial cells, dorsal ganglia neuronal cells, and myocardial cells in patients with Fabry disease, a lysosomal storage disorder characterized by a deficiency in the enzyme α-galactosidase A. Globotriaosylceramides act as natural resistance factors to HIV infection, interacting with HIV gp120 to prevent its interaction with chemokine co-receptors and subsequent fusion of HIV to host cell membranes.1 This product contains globotriaosylceramides with primarily C24:0, 2-hydroxy C24:0, and C22:0 fatty acyl chain lengths. As thisproduct is derived from a natural source, there may be variations in the sphingoid backbone.

Specifications

동의어

Globotriaosylceramide | CTH | Gb3 | 1-O-(O-α-D-galactopyranosyl-(1→4)-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranosyl)-ceramide

사양 및 순도

≥98%

보관 조건

Store at -20°C

배송

Ice chest + Ice pads

이 제품은 콜드 체인 배송이 필요합니다.지상 및 기타 경제 서비스는 사용할 수 없습니다.

작업 유형

INHIBITOR

순수함

≥98%

이름과 식별자

• 분자량: 1136.6(tetracosanoyl)

화학 및 물리적 특성

• 용해성: Soluble in chloroform/ methanol (2: 1), DMSO, and hot methanol.

자주 묻는 질문

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 71965-57-6, the molecular formula is C60H113NO18 (tetracosanoyl), and the molecular weight is 1136.6(tetracosanoyl) g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.