Chlorothiazide - Moligand™, 10mM in DMSO , Inhibitor of Na-Cl symporter, CAS No.58-94-6, Inhibitor of Na-Cl symporter

CAS: 58-94-6 Cat. No.: C408191 분자식: C₇H₆ClN₃O₄S₂ 분자량: 373.44 EC 번호: 200-404-9

GRADE & PURITY Moligand™, 10mM in DMSO

Synonyms

6-​chloro-​1,​1-​dioxide-2H-​1,​2,​4-​benzothiadiazine-​7-​sulfonamide

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

개요

Information

Chlorothiazide is a diuretic and antihypertensive. (IC50=3.8 mM)
In vitro

In vivo

Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥98%

Specifications

동의어

6-​chloro-​1,​1-​dioxide-2H-​1,​2,​4-​benzothiadiazine-​7-​sulfonamide

사양 및 순도

Moligand™, 10mM in DMSO

생화학 및 생리적 메커니즘

Chlorothiazide is a diuretic and antihypertensive. (IC50=3.8 mM)

보관 조건

Store at -80°C

배송

Dry ice packs + Cold packs

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등급

Moligand™

작업 유형

INHIBITOR

작동 메커니즘

Inhibitor of Na-Cl symporter

이름과 식별자

• 이성체 SMILES: C1=C2C(=CC(=C1Cl)S(=O)(=O)N)S(=O)(=O)N=CN2
• 분자량: 373.44
• Reaxy-Rn: 1084805
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1084805&ln=

관련 대상(인간)

SLC12A3 Tclin Solute carrier family 12 member 3 (0 Activities)

Discover Target: SLC12A3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

참고 문헌

1. Hongying Liu, Cairui Zhang, Chenwei Wang, Kai Fan, Yuqing Zhang, Lu Fang, Lihua Li, Chaoxiang Ren, Zheng-Zhi Yin, Zhong Lü.  (2023)  A highly selective and sensitive sensor for promethazine based on molecularly imprinted interface coated Au/Sn bimetal nanoclusters functionalized acupuncture needle microelectrode.  ANALYTICA CHIMICA ACTA,      [PMID:37290856] [10.1016/j.aca.2023.341395]

자주 묻는 질문

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 58-94-6, the molecular formula is C7H6ClN3O4S2, and the molecular weight is 373.44 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.