Clindamycin-13C,d3 , CAS No.2140264-63-5

CAS: 2140264-63-5 Cat. No.: C647617 분자식: C₁₇¹³CH₃₀D₃ClN₂O₅S 분자량: 428.99

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

개요

Clindamycin- 13 C,d 3 is the 13 C- and deuterium labeled Clindamycin. Clindamycin is an orally active and broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin can inhibit bacterial protein synthesis, possessing the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla). Clindamycin also can be used for researching malaria.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

Specifications

생화학 및 생리적 메커니즘

Clindamycin- 13 C,d 3 is the 13 C- and deuterium labeled Clindamycin. Clindamycin is an orally active and broad-spectrum bacteriostatic lincosamide antibiotic . Clindamycin can inhibit bacterial protein synthesis, possessing the ability to suppress the ex

보관 조건

Store at -20°C

배송

Ice chest + Ice pads

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작업 유형

INHIBITOR

이름과 식별자

• 분자량: 428.99