COG 133 TFA - ≥98% , CAS No.C658607

CAS: C658607 Cat. No.: C658607 분자식: C₉₉H₁₈₂F₃N₃₇O₂₁ 분자량: 2283.78

등급 & 순도 ≥98%

Storage

Desiccated,Store at -80°C

Shipped In

Dry ice packs + Cold packs

개요

COG 133 TFA is a fragment of Apolipoprotein E (APOE) peptide. COG 133 TFA competes with the ApoE holoprotein for binding the LDL receptor, with potent anti-inflammatory and neuroprotective effects. COG 133 TFA is also a nAChR antagonist with an IC 50 of 4

Appearance:Solid

IC50& Target:IC50: 445 nM (nAChR)

In Vivo:COG 133 (1mg/kg; intratracheal administration; every other day; for 4 weeks) treatment impairs the resolution of pulmonary fibrosis in mice. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model

Biological Activity:COG 133 TFA is a fragment of Apolipoprotein E (APOE) peptide. COG 133 TFA competes with the ApoE holoprotein for binding the LDL receptor, with potent anti-inflammatory and neuroprotective effects. COG 133 TFA is also a nAChR antagonist with an IC 50 of 4

사양

사양 및 순도

≥98%

보관 조건

Desiccated,Store at -80°C

배송

Dry ice packs + Cold packs

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작업 유형

ANTAGONIST

순수함

≥98%

이름과 식별자

분자량

2283.78

화학 및 물리적 특성

• 용해성: H2O : 50 mg/mL (21.89 mM; Need ultrasonic)