Colipase, CAS No.55126-92-6

CAS: 55126-92-6 Cat. No.: rp221826 분자량: 10 kD EC 번호: 259-490-1

GRADE & PURITY Bioactive, ActiBioPure™, EnzymoPure™, ≥4000 U/mg powder

Accession #

P02703

Bioactivity

Activity: ≥4000 U/mg powder. Specific Activity： ≥4210 U/mg protein. Definition of unit : 1U: The amount of enzyme causing the release of one micromole of fatty acid from tributyrin per minute at 25°C.

개요

Pancreatic lipase when prepared essentially free of colipase is strongly inhibited by conjugated bile salts at or above their critical micell concentration. Addition of colipase restores activity to the bile-salt-inhibited lipase and gel filtration experiments indicate that colipase in bile salt solution makes a dimer which forms a 1:1 complex with lipase.
【Properties】
Lipase and colipase interact as a stoichiometrical relationship and classified colipase interact as a co-enzyme for lipase. The colipase is a single chain polypeptide with a molecular weight approximately 11,000 with 5 disulfide bridges and isoelectric point 5.0.
【Application】
Use Colipase as a co-emulslfier in diagnostic tests for the determination of lipase activity in combination with chromogenic Lipase Substrate.
【Attention】
For your safety and health, please wear Lab coat and disposable gloves.

Specifications

Product Name

Colipase, CAS No.55126-92-6

등급

ActiBioPure™, Bioactive, EnzymoPure™

사양 및 순도

Bioactive, ActiBioPure™, EnzymoPure™, ≥4000 U/mg powder

생화학 및 생리적 메커니즘

Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.

생체 활성

Activity: ≥4000 U/mg powder. Specific Activity： ≥4210 U/mg protein. Definition of unit : 1U: The amount of enzyme causing the release of one micromole of fatty acid from tributyrin per minute at 25°C.

가입 번호

P02703

예상 분자량

11 kDa

CAS

55126-92-6

분자 유형

Enzyme

Product Line

생물 제품

보관 및 배송

집중력

≥4000 U/mg powder

보관 조건

Store at -20°C,Desiccated,Avoid repeated freezing and thawing

배송

Ice chest + Ice pads

안정성 및 스토리지

Store at -20℃ for 2 year. Avoid freeze/thaw cycle. Desiccated.

관련 대상(인간)

CLPS Tbio Colipase (0 Activities)

Discover Target: CLPS

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

자주 묻는 질문

What is ActiBioPure??

ActiBioPure? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, ActiBioPure? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

What does Bioactive mean?

Bioactive indicates that the product has been processed and tested for biological and biochemical applications. Specifications may include endotoxin limits, microbial controls, sterility, low DNase/RNase/protease activity, and verified biological activity where relevant.

How should this product be stored?

Store at ?20 °C, desiccated. Avoid repeated freeze–thaw cycles. Keep the container tightly closed with desiccant — the material is moisture-sensitive.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 55126-92-6.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.