GRADE & PURITYBioReagent?BioReagent grade — tested suitable for life-science and molecular-biology use. Use for cell culture, assays, and biochemical work needing biological compatibility.Native?Native grade — protein/biomolecule in its natural (non-recombinant, non-denatured) form. Use when native structure and activity are required.PBS Only?PBS-only formulation — supplied in phosphate-buffered saline with no other additives. Use when you need a clean PBS buffer free of stabilizers/carriers.≥85%(SDS-PAGE)Protein concentration: See COA
BioReagent,Native,PBS Only,≥85%(SDS-PAGE),Protein concentration: See COA BioReagent,Native,PBS Only for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -80°C,Avoid repeated freezing and thawing Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
개요
Complement C4 (C4) plays a central role in both the classical and lectin pathways of complement activation, with levels in human plasma ~0.4 mg/ml. C4 circulates in human plasma as a heterotrimer of 205,000 Da in plasma. The three disulfide-linked chains have molecular weights of 93 (alpha), 75 (beta), and 32 (gamma) kDa. These are readily processed to create C4a, C4b or C4c depending on the processed state.
Purity: ≥85% by SDS-PAGE.
Reacts to C4 antisera on Western Blot
Not biologically active.
Prepared from plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA-required tests.
Specifications
Product Name
Complement C4 from Human Plasma, CAS No.80295-48-3
BioReagent,Native,PBS Only,≥85%(SDS-PAGE),Protein concentration: See COA
생화학 및 생리적 메커니즘
Precursor of non-enzymatic components of the classical, lectin and GZMK complement pathways, which consist in a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system.
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