Cortagine - ≥99% , CAS No.C658697

CAS: C658697 Cat. No.: C658697 분자식: C₁₉₂H₃₂₃N₅₅O₆₃S 분자량: 4442.06

등급 & 순도 ≥99%

Storage

Desiccated,Store at -80°C

Shipped In

Dry ice packs + Cold packs

개요

Cortagine is a specific corticotropin-releasing factor receptor subtype 1 (CRF1) agonist with an EC 50 of 2.6 nM for rCRF1. Cortagine is an anxiolytic and antidepressive agent in the mouse model.

Appearance:Solid

IC50& Target:CRFR1

In Vitro:Cortagine inhibits rCRF1 (EC 50 =0.18 nM) and mCRF 2β (EC 50 =16 nM) in transfected HEK-293 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo:Cortagine (30, 100, 300 ng; i.c.v.) significantly decreases the percent time spent in the open arms and number of open arm entries of the elevated plus-maze (EPM) test in nine-week-old male C57BL/6J mice. MCE has not independently confirmed the accur

Biological Activity:Cortagine is a specific corticotropin-releasing factor receptor subtype 1 (CRF1) agonist with an EC 50 of 2.6 nM for rCRF1. Cortagine is an anxiolytic and antidepressive agent in the mouse model.

사양

사양 및 순도

≥99%

보관 조건

Desiccated,Store at -80°C

배송

Dry ice packs + Cold packs

이 제품은 콜드 체인 배송이 필요합니다.지상 및 기타 경제 서비스는 사용할 수 없습니다.

작업 유형

AGONIST

순수함

≥99%

이름과 식별자

분자량

4442.06

화학 및 물리적 특성

• 용해성: DMSO : 50 mg/mL (11.26 mM; Need ultrasonic)

자주 묻는 질문

What is the purity of this product?

This product is supplied at ≥99% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?80 °C, desiccated. Keep the container tightly closed with desiccant — the material is moisture-sensitive.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is C658697, the molecular formula is C192H323N55O63S, and the molecular weight is 4442.06 g/mol.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.