≥99% 최소한의 기준선 간섭이 필요한 민감한 크로마토그래피 및 분석 워크플로우용.
Protected from light,Store at -80°C Dry ice packs + Cold packs 출고. 정확한 사양은 로트별 COA를 확인하세요.
SDS, COA, 데이터시트, 사양서를 다운로드할 수 있습니다. 로트별 COA는 로트 번호 조회를 통해 확인할 수 있습니다.
크로마토그래피, 유기 합성 및 교차 커플링 반응 분야의 동료 심사 논문 0편에서 인용되었습니다.
CTB is a potent p300 histone acetyltransferase activator CTB can effectively induce apoptosis in MCF-7 cells .
In Vitro
CTB (10, 50, 100, 150, 200, and 250 μM; 10 min) enhances p300 HAT activity of p300 in a dosedependent manner. ?\nCTB (0-200 μM; 24 hours) inhibits the viability of MCF-7 cells with an IC 50 of 85.43 μM. ?\nCTB (85.43 μM; 24, 48 and 72 h) induces time dependence apoptosis of MCF-7 cells. ?\nCTB (50 uM; 24?h) increases p300/CBP activity , and reduces autophagic flux in primary neurons. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability AssayCell Line: MCF-7 cell Concentration: 0-200 μM Incubation Time: 24 hours Result: Inhibit viability with an IC 50 of 85.43 μM. Apoptosis AnalysisCell Line: MCF-7 cell Concentration: 85.43 μM Incubation Time: 24, 48 and 72 h Result: Iinduced time-dependence apoptosis.
Form:Solid
IC50& Target:CBP/p300
위험성, 취급, 보관 및 규제 준수를 포괄하는 종합 문서.
<<<<<<< HEAD SDS 다운로드 → ======= SDS 다운로드 → >>>>>>> release248-p3Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| 분류 | Benzene and substituted derivatives |
| Subclass | Anilides |
| Intermediate Tree Nodes | Aromatic anilides |
| Direct Parent | Benzanilides |
| Alternative Parents | Trifluoromethylbenzenes Benzamides Benzoyl derivatives Phenol ethers Phenoxy compounds Chlorobenzenes Alkyl aryl ethers Aryl chlorides Secondary carboxylic acid amides Organonitrogen compounds Organofluorides Organochlorides Organic oxides Hydrocarbon derivatives Organopnictogen compounds Alkyl fluorides |
| Molecular Framework | Aromatic homomonocyclic compounds |
| Substituents | Benzanilide - Trifluoromethylbenzene - Benzamide - Benzoic acid or derivatives - Phenoxy compound - Phenol ether - Benzoyl - Alkyl aryl ether - Chlorobenzene - Halobenzene - Aryl chloride - Aryl halide - Secondary carboxylic acid amide - Carboxamide group - Carboxylic acid derivative - Ether - Organopnictogen compound - Organofluoride - Organic oxygen compound - Organonitrogen compound - Organooxygen compound - Alkyl fluoride - Organic nitrogen compound - Hydrocarbon derivative - Organic oxide - Alkyl halide - Organochloride - Organohalogen compound - Aromatic homomonocyclic compound |
| 설명 | This compound belongs to the class of organic compounds known as benzanilides. These are aromatic compounds containing an anilide group in which the carboxamide group is substituted with a benzene ring. They have the general structure RNC(=O)R', where R,R'= benzene. |
| External Descriptors | Not available |
| 용해성 | DMSO : 100 mg/mL (290.93 mM; Need ultrasonic) |
|---|---|
| 분자량 | 343.730 g/mol |
| XLogP3 | 4.600 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 4 |
| Exact Mass | 343.059 Da |
| Monoisotopic Mass | 343.059 Da |
| Topological Polar Surface Area | 38.300 Ų |
| Heavy Atom Count | 23 |
| Formal Charge | 0 |
| Complexity | 405.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
