CUDA - ≥95% , CAS No.479413-68-8

CAS: 479413-68-8 Cat. No.: C346200 분자식: C₁₉H₃₆N₂O₃ 분자량: 340.50

등급 & 순도 ≥95%

Synonyms

12-(cyclohexylcarbamoylamino)dodecanoic acid | HY-121538 | 12-[[(cyclohexylamino)carbonyl]amino]-dodecanoic acid | DTXSID60629291 | SR-01000946808-1 | HMS3650M07 | CHEBI:181802 | BDBM129262 | US8815951, 425 | SR-01000946808 | 12-[(CYCLOHEXYLCARBAMOYL)AMIN

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

개요

CUDA is an inhibitor of soluble epoxide hydrolase (sEH, IC|50|= 11.1 nM in mice). Studies have shown that 10 μM of CUDA can block the conversion of 14,15-EET to 14,15-DHET by 94% in COS-7 cells. CUDA selectively activates peroxisome proliferator-activated receptor α (PPARα) 8-fold at a concentration of 10 μM with no affect on PPARδ or PPARγ.CUDA may be valuable for the study of cardiovascular diseases.

사양

동의어

12-(cyclohexylcarbamoylamino)dodecanoic acid | HY-121538 | 12-[[(cyclohexylamino)carbonyl]amino]-dodecanoic acid | DTXSID60629291 | SR-01000946808-1 | HMS3650M07 | CHEBI:181802 | BDBM129262 | US8815951, 425 | SR-01000946808 | 12-[(CYCLOHEXYLCARBAMOYL)AMIN

사양 및 순도

≥95%

보관 조건

Store at -20°C

배송

Ice chest + Ice pads

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작업 유형

ACTIVATOR

순수함

≥95%

이름과 식별자

Pubchem Sid

528763833

정식 스마일

C1CCC(CC1)NC(=O)NCCCCCCCCCCCC(=O)O

IUPAC Name

12-(cyclohexylcarbamoylamino)dodecanoic acid

InChIKey

HPTJABJPZMULFH-UHFFFAOYSA-N

INCHI

1S/C19H36N2O3/c22-18(23)15-11-6-4-2-1-3-5-7-12-16-20-19(24)21-17-13-9-8-10-14-17/h17H,1-16H2,(H,22,23)(H2,20,21,24)

이성체 SMILES

C1CCC(CC1)NC(=O)NCCCCCCCCCCCC(=O)O

분자량

340.50

Reaxy-Rn

9358961

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=9358961&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Lipids and lipid-like molecules
    • 분류 Fatty Acyls
      • Subclass Fatty acids and conjugates

• Kingdom: Organic compounds
• Superclass: Lipids and lipid-like molecules
• 분류: Fatty Acyls
• Subclass: Fatty acids and conjugates
• Intermediate Tree Nodes: Not available
• Direct Parent: Medium-chain fatty acids
• Alternative Parents: Amino fatty acids Ureas Monocarboxylic acids and derivatives Carboxylic acids Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic homomonocyclic compounds
• Substituents: Medium-chain fatty acid - Amino fatty acid - Urea - Monocarboxylic acid or derivatives - Carboxylic acid - Carboxylic acid derivative - Organic nitrogen compound - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Carbonyl group - Aliphatic homomonocyclic compound
• 설명: This compound belongs to the class of organic compounds known as medium-chain fatty acids. These are fatty acids with an aliphatic tail that contains between 4 and 12 carbon atoms.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

관련 대상(인간)

EPHX1 Tchem Epoxide hydrolase 1 (1 Activities)

Discover Target: EPHX1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

작용 메커니즘

화학 및 물리적 특성

• 분자량: 340.500 g/mol
• XLogP3: 5.000
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 13
• Exact Mass: 340.273 Da
• Monoisotopic Mass: 340.273 Da
• Topological Polar Surface Area: 78.400 Ų
• Heavy Atom Count: 24
• Formal Charge: 0
• Complexity: 342.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1