Cyclamic acid - Moligand™, ≥98% , Antagonist of TAS2R31;Antagonist of TAS2R43, CAS No.100-88-9, Antagonist of TAS2R31;Antagonist of TAS2R43

CAS: 100-88-9 Cat. No.: C129435 분자식: C₆H₁₃NO₃S 분자량: 179.24 Beilstein Registry Number: 2208885 EC 번호: 202-898-1

등급 & 순도 Moligand™, ≥98%

Synonyms

Cyclamic acid (USAN)|Cyclohexylamide sulfate|Cyclamsaeure|Cyclohexylamine sulfamic acid|N-Cyclohexyl-Sulfuric acid monoamide|CALCIUMLEVULINATE|cyclamic-acid|CYCLAMIC ACID [MI]|Sulfamic acid, N-cyclohexyl-|N-(Cyclohexyl)aminosulfonsaeure|Cyclohexylaminesulfonic acid|Cyclohexylsulfamic acid|cyclohexyl-sulfamic acid|Cyclamate Calcium (2:1) Salt|CYCLAMIC ACID [USAN]|Cyclohexylsulphamic acid|N-Cyclohexylsulphamic acid|N-cyclo-hexylsulphamic acid|Pharmakon1600-01301015|Cyclamic acid|Cyclohexylamine-N-sulfonic acid|Cylamic acid|Cyclamate, sodium salt|Cyclamic acid [USAN:BAN]|Cyclamate, Calcium|CYCLAMIC ACID [II]|Sulfuric acid monoamide, N-cyclohexyl-|Cyclohexylsulfamic acid;Cyclamate|Cyclohexanesulfamic acid|CYCLAMIC ACID [WHO-DD]|Cyclohexylaminesulphonic acid|Sucaryl acid|Cyclohexylamidosulphuric acid|CYCLAMATE|N-Cyclohexylsulfamic acid|n-cyclohexyl-sulfamic acid|Sulfamic acid, cyclohexyl-|Cyclamic acid|Hexamic acid|Hexamic acid (TN)|N-Cyclohexylsulfamsaeure|Cyclohexylamidosulfuric acid|INS NO.952(I)|Cyclamates|INS-952(I)|Zyklamat|CYCLAMIC ACID [MART.]|Cyclohexanesulphamic acid|Cyclamate, Potassium|Cyclohexylamide sulphate|Asugryn|CyclohexansulfamidsA currencyure|CYCLAMIC ACID [USP-RS]|Cyclamic acid, BAN, USAN|(Cyclamic Acid)

Storage

Store at 2-8°C

Shipped In

Wet ice

개요

Cyclamic acid in the form of its sodium or calcium salt is one of the most widely used artificial sweeteners.
A useful biochemical reagent.

사양

동의어

Cyclamic acid (USAN) | Cyclohexylamide sulfate | Cyclamsaeure | Cyclohexylamine sulfamic acid | N-Cyclohexyl-Sulfuric acid monoamide | CALCIUMLEVULINATE | cyclamic-acid | CYCLAMIC ACID [MI] | Sulfamic acid, N-cyclohexyl- | N-(Cyclohexyl)aminosulfonsaeure | Cyclohexylaminesulfonic acid | Cyclohexylsulfamic acid | cyclohexyl-sulfamic acid | Show more

사양 및 순도

Moligand™, ≥98%

생화학 및 생리적 메커니즘

A non-nutritive sweetener.Potent TAS 1 R 3 ligand. Binds to the transmembrane domain of TAS 1 R 3 . Action is unaffected by umami compounds. Putative carcinogenic agent in vivo. Orally active.

보관 조건

Store at 2-8°C

배송

Wet ice

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등급

Moligand™

작업 유형

ANTAGONIST

작동 메커니즘

Antagonist of TAS2R31;Antagonist of TAS2R43

참고

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

순수함

≥98%

이름과 식별자

Pubchem Sid

504751385

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/504751385

정식 스마일

C1CCC(CC1)NS(=O)(=O)O

IUPAC Name

cyclohexylsulfamic acid

InChIKey

HCAJEUSONLESMK-UHFFFAOYSA-N

INCHI

1S/C6H13NO3S/c8-11(9,10)7-6-4-2-1-3-5-6/h6-7H,1-5H2,(H,8,9,10)

이성체 SMILES

C1CCC(CC1)NS(=O)(=O)O

WGK 독일

2

RTECS

GV6950000

대체 CAS

100-88-9

NSC 번호

220327

MeSH 용어

Calcium Cyclamate;Cyclamate;Cyclamate Calcium (2:1) Salt;Cyclamate, Calcium;Cyclamate, Calcium (2:1) Salt, Dihydrate;Cyclamate, Potassium;Cyclamate, Sodium;Cyclamate, Sodium Salt;Cyclamates;Cyclamic Acid;Potassium Cyclamate;Sodium Cyclamate

분자량

179.24

Beilstein

2208885

Reaxy-Rn

2208885

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2208885&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • 분류 Sulfamic acid derivatives
      • Subclass Cyclamates

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• 분류: Sulfamic acid derivatives
• Subclass: Cyclamates
• Intermediate Tree Nodes: Not available
• Direct Parent: Cyclamates
• Alternative Parents: Sulfuric acid monoamides Organopnictogen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aliphatic homomonocyclic compounds
• Substituents: Cyclamic_acid_derivative - Sulfuric acid monoamide - Organic sulfuric acid or derivatives - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organonitrogen compound - Aliphatic homomonocyclic compound
• 설명: This compound belongs to the class of organic compounds known as cyclamates. These are compounds containing a cyclohexylsulfamic acid moiety.
• External Descriptors: sulfamic acids

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

관련 대상(인간)

TAS2R43 Tchem Taste receptor type 2 member 43 (0 Activities)

Discover Target: TAS2R43

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TAS2R31 Tchem Taste receptor type 2 member 31 (0 Activities)

Discover Target: TAS2R31

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TAS1R2 Tbio Taste receptor type 1 member 2 (15 Activities)

Discover Target: TAS1R2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TAS1R3 Tbio Taste receptor type 1 member 3 (10 Activities)

Discover Target: TAS1R3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TAS2R31 Tchem Taste receptor type 2 member 31 (86 Activities)

Discover Target: TAS2R31

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TAS1R3 Tbio T1R1/T1R3 (473 Activities)

Discover Target: TAS1R3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

관련 대상(비인간)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Plasmodium falciparum (966862 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Chrm1 Muscarinic acetylcholine receptor (3770 Activities)

Discover Target: Chrm1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

작용 메커니즘

화학 및 물리적 특성

• 용해성: DMSO 36 mg/mL Water 36 mg/mL Ethanol 36 mg/mL
• 녹는점(°C): 169 °C(dec.)
• 분자량: 179.240 g/mol
• XLogP3: 0.600
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 179.062 Da
• Monoisotopic Mass: 179.062 Da
• Topological Polar Surface Area: 74.800 Ų
• Heavy Atom Count: 11
• Formal Charge: 0
• Complexity: 200.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

자주 묻는 질문

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at 2–8 °C. Refrigerated storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships chilled on wet ice. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 100-88-9, the molecular formula is C6H13NO3S, and the molecular weight is 179.24 g/mol. InChIKey HCAJEUSONLESMK-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.