Cyclamic acid - Moligand™, 10mM in DMSO , Antagonist of TAS2R31;Antagonist of TAS2R43, CAS No.100-88-9, Antagonist of TAS2R31;Antagonist of TAS2R43

CAS: 100-88-9 Cat. No.: C408450 분자식: C₆H₁₃NO₃S 분자량: 179.24 Beilstein Registry Number: 2208885 EC 번호: 202-898-1

등급 & 순도 Moligand™, 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

개요

Information

Cyclamic acid (NSC 220327) in the form of its sodium or calcium salt is one of the most widely used artificial sweeteners.
In vitro

Cyclamic acid in the form of its sodium or calcium salt is one of the most widely used artificial sweeteners in food and pharmaceuticals. Cyclamic acid is in use in more than 50 countries, especially in combination with other sweeteners, to eliminate aftertaste. However, the petition on Cyclamic acid, calcium and sodium cyclamate is being held in abeyance with the FDA in the USA (CFSAN - Office of Food Additive Safety, 2006).

In vivo

Cell Data

cell lines：BaF3.TPR-MET, H69 and H345 cells

Concentrations：

Incubation Time：

Powder Purity:

사양

사양 및 순도

Moligand™, 10mM in DMSO

생화학 및 생리적 메커니즘

A non-nutritive sweetener.Potent TAS 1 R 3 ligand. Binds to the transmembrane domain of TAS 1 R 3 . Action is unaffected by umami compounds. Putative carcinogenic agent in vivo. Orally active.

보관 조건

Store at -80°C

배송

Dry ice packs + Cold packs

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등급

Moligand™

작업 유형

ANTAGONIST

작동 메커니즘

Antagonist of TAS2R31;Antagonist of TAS2R43

이름과 식별자

이성체 SMILES

C1CCC(CC1)NS(=O)(=O)O

WGK 독일

2

RTECS

GV6950000

대체 CAS

100-88-9

NSC 번호

220327

MeSH 용어

Calcium Cyclamate;Cyclamate;Cyclamate Calcium (2:1) Salt;Cyclamate, Calcium;Cyclamate, Calcium (2:1) Salt, Dihydrate;Cyclamate, Potassium;Cyclamate, Sodium;Cyclamate, Sodium Salt;Cyclamates;Cyclamic Acid;Potassium Cyclamate;Sodium Cyclamate

분자량

179.24

Beilstein

2208885

Reaxy-Rn

2208885

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2208885&ln=

관련 대상(인간)

TAS2R43 Tchem Taste receptor type 2 member 43 (0 Activities)

Discover Target: TAS2R43

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TAS2R31 Tchem Taste receptor type 2 member 31 (0 Activities)

Discover Target: TAS2R31

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

화학 및 물리적 특성

• 녹는점(°C): 169 °C(dec.)

자주 묻는 질문

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 100-88-9, the molecular formula is C6H13NO3S, and the molecular weight is 179.24 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.