Cycloheximide (NSC-185) - Moligand™, 10mM in DMSO , 80S Ribosome inhibitor, CAS No.66-81-9, 80S Ribosome inhibitor

CAS: 66-81-9 Cat. No.: C408230 분자식: C₁₅H₂₃NO₄ 분자량: 281.35 EC 번호: 200-636-0

등급 & 순도 Moligand™, 10mM in DMSO

Synonyms

Actidione, Naramycin A, CHX, FT 3422-2, NM-MCD 80 | 4-[2-(3,5-Dimethyl-2-oxo-cyclohexyl)-2-hydroxyethyl]-2,6-piperidinedione

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs,FedEx DG Service

개요

Information

Cycloheximide (NSC-185) Cycloheximide (NSC-185, Actidione, Naramycin A, CHX, FT 3422-2, NM-MCD 80), an antifungal antibiotic, is an eukaryote protein synthesis inhibitor with IC50 of 532.5 nM and 2880 nM for protein synthesis and RNA synthesis in vivo,
In vitro

In vivo

Cell Data

cell lines：HT29, Colo205, PC-3, MDA-MB-231 and K562 cells

Concentrations：

Incubation Time：

Powder Purity:≥97%

사양

동의어

Actidione, Naramycin A, CHX, FT 3422-2, NM-MCD 80 | 4-[2-(3,5-Dimethyl-2-oxo-cyclohexyl)-2-hydroxyethyl]-2,6-piperidinedione

사양 및 순도

Moligand™, 10mM in DMSO

생화학 및 생리적 메커니즘

Cycloheximide (NSC-185, Actidione, Naramycin A, CHX, FT 3422-2, NM-MCD 80), an antifungal antibiotic, is an eukaryote protein synthesis inhibitor with IC50 of 532.5 nM and 2880 nM for protein synthesis and RNA synthesis in vivo, respectively. Cycloheximid

보관 조건

Store at -80°C

배송

Dry ice packs + Cold packs,FedEx DG Service

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등급

Moligand™

작업 유형

INHIBITOR

작동 메커니즘

80S Ribosome inhibitor

제품 특성

ALogP

0.5

이름과 식별자

이성체 SMILES

C[C@H]1C[C@@H](C(=O)[C@@H](C1)[C@@H](CC2CC(=O)NC(=O)C2)O)C

UN 번호

2811

포장 그룹

II

분자량

281.35

Reaxy-Rn

9515475

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=9515475&ln=

관련 대상(인간)

EIF4A1 Tchem Eukaryotic initiation factor 4A-I (0 Activities)

Discover Target: EIF4A1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SLC2A1 Tchem Solute carrier family 2, facilitated glucose transporter member 1 (0 Activities)

Discover Target: SLC2A1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

화학 및 물리적 특성

• 용해성: Solubility (25°C) In vitro DMSO: 53 mg/mL (79.62 mM); Water: Insoluble; Ethanol: Insoluble
• 발화점(°F): 230°F
• 발화점(°C): >110°C
• 끓는점(°C): 492°C
• 녹는점(°C): 119.5-121°C

자주 묻는 질문

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 66-81-9, the molecular formula is C15H23NO4, and the molecular weight is 281.35 g/mol.

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.