Cyclosomatostatin - ≥97% , CAS No.84211-54-1

CAS: 84211-54-1(Free base) Cat. No.: C275432 분자식: C₄₆H₅₈F₃N₇O₈ 분자량: 893.99

GRADE & PURITY Moligand™, ≥97%

Synonyms

CPP1 | L-Threonine, N-(7-amino-1-oxoheptyl)-L-phenylalanyl-D-tryptophyl-L-lysyl-O-(phenylmethyl)-, (2S-(1(R*(R*)),2alpha,3abeta,7abeta))- | CyCam | Cyclo-(7-aminoheptanoyl-Phe-D-Trp-Lys-Thr[BZL]) | AKOS024457638 | Antagonist srif-A | Cyclo-(7-aminoheptano

Storage

Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

개요

Cyclosomatostatin TFA is a potent somatostatin (SST) receptor antagonist. Cyclosomatostatin (TFA) can inhibit somatostatin receptor type 1 (SSTR1) signaling and decreases cell proliferation, ALDH+ cell population size and sphere-formation in colorectal cancer (CRC) cells.

Specifications

동의어

CPP1 | L-Threonine, N-(7-amino-1-oxoheptyl)-L-phenylalanyl-D-tryptophyl-L-lysyl-O-(phenylmethyl)-, (2S-(1(R*(R*)),2alpha,3abeta,7abeta))- | CyCam | Cyclo-(7-aminoheptanoyl-Phe-D-Trp-Lys-Thr[BZL]) | AKOS024457638 | Antagonist srif-A | Cyclo-(7-aminoheptano

사양 및 순도

Moligand™, ≥97%

생화학 및 생리적 메커니즘

Somatostatin antagonist with various biological activities. Blocks the effect of somatostatin on β-adrenergic function and CRF-induced suppression of gastric empyting, ACh release and growth hormone, insulin, and Glukagon release.

보관 조건

Store at -20°C,Desiccated

배송

Ice chest + Ice pads

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등급

Moligand™

작업 유형

ANTAGONIST

참고

This product is supplied in one (or more) pack size which is freeze dried. Therefore the contents may not be readily visible, as they can coat the bottom or walls of the vial. Please see our FAQs and information page for more details on handling. Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

순수함

≥97%

이름과 식별자

정식 스마일

CC(C1C(=O)NCCCCCCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=CC=C4)OCC5=CC=CC=C5

IUPAC Name

(3S,6S,9R,12S)-6-(4-aminobutyl)-12-benzyl-9-(1H-indol-3-ylmethyl)-3-[(1R)-1-phenylmethoxyethyl]-1,4,7,10,13-pentazacycloicosane-2,5,8,11,14-pentone

InChIKey

YHVHQZYJGWGAKN-ZUWUZHNASA-N

INCHI

1S/C44H57N7O6/c1-30(57-29-32-18-8-5-9-19-32)40-44(56)46-25-15-3-2-10-23-39(52)48-37(26-31-16-6-4-7-17-31)42(54)50-38(27-33-28-47-35-21-12-11-20-34(33)35)43(55)49-36(41(53)51-40)22-13-14-24-45/h4-9,11-12,16-21,28,30,36-38,40,47H,2-3,10,13-15,22-27,29,45H2,1H3,(H,46,56)(H,48,52)(H,49,55)(H,50,54)(H,51,53)/t30-,36+,37+,38-,40+/m1/s1

분자량

893.99

화학 및 물리적 특성

• 용해성: Soluble in DMSO to 1mg/ml
• 감도: Moisture sensitive
• 분자량: 780.000 g/mol
• XLogP3: 4.300
• Hydrogen Bond Donor Count: 7
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 12
• Exact Mass: 779.437 Da
• Monoisotopic Mass: 779.437 Da
• Topological Polar Surface Area: 197.000 Ų
• Heavy Atom Count: 57
• Formal Charge: 0
• Complexity: 1270.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 5
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

자주 묻는 질문

What is the purity of this product?

This product is supplied at ≥97% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C, desiccated. Keep the container tightly closed with desiccant — the material is moisture-sensitive.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 84211-54-1, the molecular formula is C44H57N7O6, and the molecular weight is 779.97 g/mol. InChIKey YHVHQZYJGWGAKN-ZUWUZHNASA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.