Cytochalasin J - ≥95% , CAS No.53760-20-6

CAS: 53760-20-6 Cat. No.: C329406 분자식: C₂₈H₃₇NO₄ 분자량: 451.6 EC 번호: 637-306-4 PubChem CID: 102239810

GRADE & PURITY ≥95%

Synonyms

(1R,2R,3Z,5R,7S,9Z,11R,12S,14S,15R,16S)-16-benzyl-2,5,12-trihydroxy-5,7,14-trimethyl-13-methylidene-17-azatricyclo[9.7.0.01,15]octadeca-3,9-dien-18-one | Cytochalasin j

Storage

Protected from light,Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

개요

Cytochalasin J is used in actin polymerization studies. Cytochalasins are potent mycotoxins which bind to the barbed end of actin filaments resulting in inhibition of both the association and dissociation of subunits. Used as a tool for cytological research. These fungal toxins are related by their chemical structure characterized by a highly substituted hydrogenated isoindole ring to which is fused a macrocyclic ring. Cytochalasin J is the deacetyl analogue of cytochalasin H and exhibits similar, though less potent, antibacterial, antifungal, nematocidal and antitumor activities.

Application：

Cytochalasin J is a cell-permeable fungal toxin used in actin polymerization studies and cytological research

Specifications

동의어

(1R,2R,3Z,5R,7S,9Z,11R,12S,14S,15R,16S)-16-benzyl-2,5,12-trihydroxy-5,7,14-trimethyl-13-methylidene-17-azatricyclo[9.7.0.01,15]octadeca-3,9-dien-18-one | Cytochalasin j

사양 및 순도

≥95%

보관 조건

Protected from light,Store at -20°C,Argon charged

배송

Ice chest + Ice pads

이 제품은 콜드 체인 배송이 필요합니다.지상 및 기타 경제 서비스는 사용할 수 없습니다.

참고

Cytochalasins are regarded as highly toxic and possible teratogens. Handle in a manner to avoid/minimize direct body contact and inhalation.

순수함

≥95%

이름과 식별자

Pubchem Sid

488202606

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/488202606

정식 스마일

CC1CC=CC2C(C(=C)C(C3C2(C(C=CC(C1)(C)O)O)C(=O)NC3CC4=CC=CC=C4)C)O

IUPAC Name

(1R,2R,3Z,5R,7S,9Z,11R,12S,14S,15R,16S)-16-benzyl-2,5,12-trihydroxy-5,7,14-trimethyl-13-methylidene-17-azatricyclo[9.7.0.01,15]octadeca-3,9-dien-18-one

InChIKey

UKQNIEMKORIOQM-RVVPKKHWSA-N

INCHI

1S/C28H37NO4/c1-17-9-8-12-21-25(31)19(3)18(2)24-22(15-20-10-6-5-7-11-20)29-26(32)28(21,24)23(30)13-14-27(4,33)16-17/h5-8,10-14,17-18,21-25,30-31,33H,3,9,15-16H2,1-2,4H3,(H,29,32)/b12-8-,14-13-/t17-,18+,21-,22-,23+,24-,25+,27-,28+/m0/s1

이성체 SMILES

C[C@H]1C/C=C\[C@H]2[C@@H](C(=C)[C@H]([C@@H]3[C@@]2([C@@H](/C=C\[C@](C1)(C)O)O)C(=O)N[C@H]3CC4=CC=CC=C4)C)O

WGK 독일

3

PubChem CID

102239810

분자량

451.6

화학 및 물리적 특성

• 용해성: Soluble in ethanol, methanol, DMF, DMSO, and water (poorly).
• 감도: Light sensitive
• 굴절률: n20D1.61 (Predicted)
• 끓는점(°C): 679.51° C at 760 mmHg (Predicted)
• 녹는점(°C): 137-139° C